Dynamics of bubbles and ultrasound: Diagnostic imaging to blood pressure monitoring and tissue engineering
Kausik Sarkar
Phys. Rev. Fluids 10, 030501 (2025) - Published 17 March, 2025
Observations of ultrasound interacting with coated microbubbles has become an important biomedical tool for diagnostic imaging and therapeutics. This paper presents a perspective which highlights the underlying linear and nonlinear bubble dynamics. Mathematical modeling of contrast microbubbles, including an interfacial rheological model, and model building and improvement using attenuation and scattering experiments are presented. A method of noninvasive organ-level blood pressure monitoring is described. Microbubbles together with low-intensity pulsed ultrasound are also demonstrated to be an effective tool in tissue engineering.
Fluid mechanical study of rotation-induced traumatic brain injury
Qifu Wang, Jiaqi Zhang, David Bates, James J. Feng, Pengtao Yue, and Qianhong Wu
Phys. Rev. Fluids 10, 030502 (2025) - Published 28 March, 2025
Rotation-induced traumatic brain injury is a serious health concern. We present a novel experimental and theoretical approach to studying fluid-structure interactions between soft matter and its liquid surroundings under rapid rotational impact. Our theoretical model, developed using the Arbitrary Lagrangian-Eulerian method, has been verified and validated against experimental data. This work establishes a strong foundation for future research into rotation-induced brain concussions, where the transient fluid-structure interaction between the cerebrospinal fluid and the soft brain matter plays a critical role in impact transmission and mitigation.











































