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HIGHLIGHTED ARTICLES

Connecting cooperative transport by ants with the physics of self-propelled particles

Tabea Heckenthaler, Tobias Holder, Ariel Amir, Ofer Feinerman, and Ehud Fonio

PRX Life 1, 023001 (2023) - Published 5 October, 2023

Drawing from the physics of self-propelled particles, the authors introduce a macroscopic model to describe their experiments on ants’ cooperative transport. They connected this to previous coupled-carrier models, bridging the gap from micro to macro scales.

Tension Remodeling Regulates Topological Transitions in Epithelial Tissues

Fernanda Pérez-Verdugo and Shiladitya Banerjee

PRX Life 1, 023006 (2023) - Published 27 November, 2023

In this work, authors introduce a dynamic vertex model incorporating strain-induced tension remodeling and mechanical memory dissipation to explain topological transitions commonly observed in epithelial tissues.

ARTICLES

Connecting cooperative transport by ants with the physics of self-propelled particles

Tabea Heckenthaler, Tobias Holder, Ariel Amir, Ofer Feinerman, and Ehud Fonio

PRX Life 1, 023001 (2023) - Published 5 October, 2023

Drawing from the physics of self-propelled particles, the authors introduce a macroscopic model to describe their experiments on ants’ cooperative transport. They connected this to previous coupled-carrier models, bridging the gap from micro to macro scales.

Odd Elastohydrodynamics: Non-Reciprocal Living Material in a Viscous Fluid

Kenta Ishimoto, Clément Moreau, and Kento Yasuda

PRX Life 1, 023002 (2023) - Published 11 October, 2023

This study expands the odd-elastic description of microswimmers to a nonlinear regime and provides a unified framework for studying non-local, non-reciprocal interactions of an elastic material in a viscous fluid, like biological flagellar motion.

Semantic Information in a Model of Resource Gathering Agents

Damian R. Sowinski, Jonathan Carroll-Nellenback, Robert N. Markwick, Jordi Piñero, Marcelo Gleiser, Artemy Kolchinsky, Gourab Ghoshal, and Adam Frank

PRX Life 1, 023003 (2023) - Published 17 October, 2023

In this study, resource foraging is analyzed using the framework of “Semantic Information theory” predicting a sharp transition in the forager’s expected lifetime as correlations with the environment are scrambled.

Emergence of Single- versus Multi-State Allostery

Eric Rouviere, Rama Ranganathan, and Olivier Rivoire

PRX Life 1, 023004 (2023) - Published 9 November, 2023

In this study, the authors introduce an abstract model that describes the origins of multi- and single-state protein allostery, demonstrating how evolution might favor the former.

Information Bottleneck in Molecular Sensing

Marianne Bauer and William Bialek

PRX Life 1, 023005 (2023) - Published 15 November, 2023

Molecular interactions at low concentrations transmit information with low capacity; this study explores how universal features of this bottleneck influence the representation of positional information by the gap genes in the fly embryo.

Tension Remodeling Regulates Topological Transitions in Epithelial Tissues

Fernanda Pérez-Verdugo and Shiladitya Banerjee

PRX Life 1, 023006 (2023) - Published 27 November, 2023

In this work, authors introduce a dynamic vertex model incorporating strain-induced tension remodeling and mechanical memory dissipation to explain topological transitions commonly observed in epithelial tissues.

Interplay Between Mechanosensitive Adhesions and Membrane Tension Regulates Cell Motility

Yuzhu Chen, David Saintillan, and Padmini Rangamani

PRX Life 1, 023007 (2023) - Published 6 December, 2023

This study presents a model of cell motility that explains the initiation of cell motion by a symmetry-breaking instability and reveals that complex cell behaviors - from motility to shape selection - are governed by dynamic activities at the cell edge.

Spontaneous Rotation of Active Droplets in Two and Three Dimensions

Mehrana R. Nejad and Julia M. Yeomans

PRX Life 1, 023008 (2023) - Published 14 December, 2023

This research reveals that living particle aggregates rotate spontaneously due to defect formation and identifies a critical droplet size where order evolves into turbulence, as observed in experiments.

Models of Cell Processes are Far from the Edge of Chaos

Kyu Hyong Park, Felipe Xavier Costa, Luis M. Rocha, Réka Albert, and Jordan C. Rozum

PRX Life 1, 023009 (2023) - Published 15 December, 2023

In this study, novel metrics and simulations of experimentally-supported discrete dynamical models of cell processes reveal greater resilience to perturbation than previously observed, challenging the ‘edge of chaos’ theory for biological systems.

Actin and Microtubules Position Stress Granules

Thomas J. Böddeker, Anja Rusch, Keno Leeners, Michael P. Murrell, and Eric R. Dufresne

PRX Life 1, 023010 (2023) - Published 19 December, 2023

Novel analysis tools reveal that stress granules show different affinities to filamentous actin and microtubules, leading to robust stress granule positioning through coupling to actin flow and wetting of microtubules.

Mapping Stochastic Collective Behavior Distinguishes Subtle Mutations in Social Bacteria

Merrill E. Asp, Eduardo A. Caro, Roy D. Welch, and Alison E. Patteson

PRX Life 1, 023011 (2023) - Published 21 December, 2023

In this study, the authors introduce a high-throughput imaging technique to investigate the influence of subtle genetic mutations on the multicellular organization of Myxococcus xanthus under controlled environmental conditions.

Robust Retrieval of Dynamic Sequences through Interaction Modulation

Lukas Herron, Pablo Sartori, and BingKan Xue

PRX Life 1, 023012 (2023) - Published 22 December, 2023

In this study, interaction modulation is proposed as a new paradigm for controlling transitions between functional configurations of complex biological systems, in contrast to traditional approaches based on input modulation.

Impact of Linker Length on Biomolecular Condensate Formation

Trevor GrandPre, Yaojun Zhang, Andrew G. T. Pyo, Benjamin Weiner, Je-Luen Li, Martin C. Jonikas, and Ned S. Wingreen

PRX Life 1, 023013 (2023) - Published 26 December, 2023

Using the algal Rubisco-EPYC1 system as a model for biomolecular condensates, this study shows that the length of linker regions between interacting domains on phase-separating proteins can dramatically impact entropic costs and the propensity to form condensates.

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