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Scanning tunneling conductance map of a superconducting vortex lattice, with its corresponding Fourier transform in the inset.

From the article:

Robust Two-Dimensional Surface Superconductivity and Vortex Lattice in the Weyl Semimetal γPtBi2
Jose Antonio Moreno, Pablo García Talavera, Edwin Herrera, Sara López Valle, Zhuoqi Li, Lin-Lin Wang, Sergey Bud’ko, Alexander I. Buzdin, Isabel Guillamón, Paul C. Canfield, and Hermann Suderow
Phys. Rev. Lett. 137, 086001 (2026)

HIGHLIGHTED ARTICLES

Hundred-Channel Reconfigurable Quantum Teleportation

Yanbo Lou, Jiabin Wang, Yuyan Zou, Lingyue Hou, Shengshuai Liu, and Jietai Jing

Phys. Rev. Lett. 137, 080801 (2026) - Published 20 August, 2026

Researchers have demonstrated the quantum teleportation of a 100-pixel image by a method that could help to scale up quantum networks.

Multiple Phases in K2Cr3As3: A Playground for Manipulating Topological Superconductivity

Seigo Ogawa, Tomoki Miyoshi, Saki Uchida, Kazuaki Matano, Shinji Kawasaki, Yoshihiko Inada, and Guo-qing Zheng

Phys. Rev. Lett. 137, 086003 (2026) - Published 19 August, 2026

Researchers have made the first definitive measurements of an elusive superconducting state.

Robust Two-Qubit Geometric Phase Gates Using Amplitude and Frequency Ramping

C. M. Bowers, D. Palani, J. J. Barta, T. H. Guglielmo, S. B. Libby, D. Leibfried, and D. H. Slichter

Phys. Rev. Lett. 137, 080602 (2026) - Published 20 August, 2026

Adiabatic ramping of both state-dependent force amplitude and motional frequency delivers high-fidelity trapped-ion entanglement without ground-state cooling.

Complete-Coverage Searches for Lorentz Violation in the Minimal Matter Sector

Marshall J. Basson, Eric Biddulph-West, Caitlyn Holl, Will Lankenau, Facundo Martin Lopez, Bianca Rose Lott, Chihui Shao, Danny P. Shope, Jay D. Tasson, and Zhiyu Zhang

Phys. Rev. Lett. 137, 081601 (2026) - Published 17 August, 2026

All 43 previously unconstrained Lorentz-violating degrees of freedom in the minimal matter sector are constrained for the first time, completing a decades-long program.

Evidence of Nuclear Geometry-Driven Anisotropic Flow in O+O and Ne+Ne Collisions at sNN=5.36TeV

I. J. Abualrob et al. (ALICE Collaboration)

Phys. Rev. Lett. 137, 082301 (2026) - Published 17 August, 2026

Light-ion collisions at the LHC reveal collective hydrodynamic flow with a larger elliptic flow in central Ne-Ne collisions than in OO collisions that might be due to the bowling-pin nuclear shape of 20Ne.

Observation of Long-Range Collective Flow in O+O and Ne+Ne Collisions and Implications for Nuclear Structure Studies

A. Hayrapetyan et al. (CMS Collaboration)

Phys. Rev. Lett. 137, 082302 (2026) - Published 17 August, 2026

Light-ion collisions at the LHC reveal collective hydrodynamic flow with a larger elliptic flow in central Ne-Ne collisions than in OO collisions that might be due to the bowling-pin nuclear shape of 20Ne.

Deformation and Magicity in Heavy Actinides: First Observation of the Ground-State Rotational Band of Fm252

R. Orlandi et al.

Phys. Rev. Lett. 137, 082501 (2026) - Published 17 August, 2026

Observation of the ground-state rotational band in 252Fm provides compelling evidence that Z=100 and N=152 act as a deformed doubly magic shell closure.

Evaporative Flux Reversal of Binary Droplets: From Edge to Apex

Minhyeok Kuk and Hyoungsoo Kim

Phys. Rev. Lett. 137, 084002 (2026) - Published 20 August, 2026

Experimental studies of multicomponent droplet evaporation reveal distinct stages, with internal flow shifting from multiple vortices within the droplet to a single toroidal vortex dominating the flow dynamic, departing from the classical single-component picture.

Robust Two-Dimensional Surface Superconductivity and Vortex Lattice in the Weyl Semimetal γPtBi2

Jose Antonio Moreno, Pablo García Talavera, Edwin Herrera, Sara López Valle, Zhuoqi Li, Lin-Lin Wang, Sergey Bud’ko, Alexander I. Buzdin, Isabel Guillamón, Paul C. Canfield, and Hermann Suderow

Phys. Rev. Lett. 137, 086001 (2026) - Published 17 August, 2026

Vortex formation from surface superconductivity is observed in the topological semimetal γ-PtBi2, which confirms the robustness of the surface superconductivity at a higher Tc than the bulk.

Heterostructuring as Gateway to Electron Doping of Nickelate Superconductors

Chao Deng, Motoharu Kitatani, Guiwen Jiang, Siqi Guo, Niklas Witt, Ao Zhang, Wenfeng Wu, Mi Jiang, Karsten Held, and Liang Si

Phys. Rev. Lett. 137, 086004 (2026) - Published 20 August, 2026

Intercalation-driven self-doping is a general mechanism for engineering high-temperature superconductivity and emergent quantum states in Ruddlesden–Popper phase correlated oxides.

Spin Stripes and Superconductivity in Bilayer Nickelates

Hao-Xin Wang, Hanbit Oh, Tobias Helbig, Bai Yang Wang, Jiarui Li, Yijun Yu, Harold Y. Hwang, Hong-Chen Jiang, Yi-Ming Wu, and S. Raghu

Phys. Rev. Lett. 137, 086502 (2026) - Published 18 August, 2026

Density matrix renormalization group calculations reveal spin-stripe ordering at large Hund’s coupling, demonstrating that Hund’s coupling and inter-layer coupling are key parameters in magnetic order and pairing.

Room-Temperature Noncollinear Ferroelectricity in van der Waals WO2Cl2 with a Wide Bandgap

Yu Xing, Ning Ding, Zhipeng Wang, Zhiwen Pan, Lei Guo, Guowei Du, Yangrui Liu, Xiaoxing Cao, Ran Su, Mengting Jiang, Xuezhi Ma, Xiyu Chen, Junchao Zhang, Xinyu Yang, Haoran Ye, Honghong Yao, Rui Feng, Dexiang Chen, Le-Ping Miao, Yumeng You, Zejun Li, Dongsheng Song, Linglong Li, and Shuai Dong

Phys. Rev. Lett. 137, 086801 (2026) - Published 21 August, 2026

Exotic noncollinear room-temperature ferroelectricity has now been experimentally realized in 2D WO2Cl2, establishing a polar counterpart to noncollinear spin textures.

Quantitative and Predictive Folding Models from Limited Single-Molecule Data Using Simulation-Based Inference

Lars Dingeldein, Aaron Lyons, Pilar Cossio, Michael T. Woodside, and Roberto Covino

Phys. Rev. Lett. 137, 088402 (2026) - Published 19 August, 2026

A simulation-based inference framework combines physics-based modeling with deep learning to recover the Bayesian posterior of a biomolecular folding model directly from single-molecule force spectroscopy data.

LETTERS

Quantum Information, Science, and Technology

Extendibility of Fermionic Gaussian States

Amir-Reza Negari and Farzin Salek

Phys. Rev. Lett. 137, 080201 (2026) - Published 18 August, 2026

Testing the Equivalence to Thermal States via Extractable Work under Local Operations and Classical Communication

Toshihiro Yada, Nobuyuki Yoshioka, and Takahiro Sagawa

Phys. Rev. Lett. 137, 080401 (2026) - Published 21 August, 2026

Kirkwood-Dirac Nonpositivity Is a Necessary Resource for Quantum Computing

Jonathan J. Thio, Songqinghao Yang, Nicole Yunger Halpern, Stephan De Bièvre, Crispin H. W. Barnes, and David R. M. Arvidsson-Shukur

Phys. Rev. Lett. 137, 080601 (2026) - Published 18 August, 2026

Robust Two-Qubit Geometric Phase Gates Using Amplitude and Frequency Ramping

C. M. Bowers, D. Palani, J. J. Barta, T. H. Guglielmo, S. B. Libby, D. Leibfried, and D. H. Slichter

Phys. Rev. Lett. 137, 080602 (2026) - Published 20 August, 2026

Adiabatic ramping of both state-dependent force amplitude and motional frequency delivers high-fidelity trapped-ion entanglement without ground-state cooling.

Enhancing Image Recognition Using Gaussian Boson Sampling

Si-Qiu Gong, Ming-Cheng Chen, Hua-Liang Liu, Hao Su, Yi-Chao Gu, Hao-Yang Tang, Meng-Hao Jia, Yu-Hao Deng, Han-Tao Sun, Qian Wei, Hui Wang, Han-Sen Zhong, Xiao Jiang, Li Li, Nai-Le Liu, Dong-Ling Deng, Chao-Yang Lu, and Jian-Wei Pan

Phys. Rev. Lett. 137, 080603 (2026) - Published 20 August, 2026

Hundred-Channel Reconfigurable Quantum Teleportation

Yanbo Lou, Jiabin Wang, Yuyan Zou, Lingyue Hou, Shengshuai Liu, and Jietai Jing

Phys. Rev. Lett. 137, 080801 (2026) - Published 20 August, 2026

Researchers have demonstrated the quantum teleportation of a 100-pixel image by a method that could help to scale up quantum networks.

Cosmology, Astrophysics, and Gravitation

Stringent Constraints on Spin-Spin-Velocity-Dependent Exotic Interactions with a Levitated Magnet Force Sensor

Kenan Tian, Siwen Chen, Lei Wang, Yuanji Sheng, Dingjiang Long, Rui Li, Han Xie, Yiming Chen, Xiang Bian, Hao Wang, Ruoyu Ding, Chang-Kui Duan, Peiran Yin, Xi Kong, and Pu Huang

Phys. Rev. Lett. 137, 081001 (2026) - Published 17 August, 2026

Characterization of the Three-Flavor Composition of Cosmic Neutrinos with IceCube

R. Abbasi et al. (IceCube Collaboration)

Phys. Rev. Lett. 137, 081002 (2026) - Published 18 August, 2026

Constraints on Large-Scale White Noise in the Cosmic Density Field

Gabriela Barenboim, Aurora Ireland, and Albert Stebbins

Phys. Rev. Lett. 137, 081003 (2026) - Published 18 August, 2026

Free-Streaming Length of Dark Matter from JWST Observations of 28 Strong Gravitational Lenses

D. Gilman et al.

Phys. Rev. Lett. 137, 081004 (2026) - Published 18 August, 2026

High Post-Minkowskian Gravitational Waveform for Hyperbolic Encounters in the Extreme-Mass-Ratio Limit

Andrea Geralico

Phys. Rev. Lett. 137, 081401 (2026) - Published 18 August, 2026

Conservative Black Hole Scattering at Fifth Post-Minkowskian and Second Self-Force Order

Mathias Driesse, Gustav Uhre Jakobsen, Gustav Mogull, Christoph Nega, Jan Plefka, Benjamin Sauer, and Johann Usovitsch

Phys. Rev. Lett. 137, 081402 (2026) - Published 21 August, 2026

Particles and Fields

Complete-Coverage Searches for Lorentz Violation in the Minimal Matter Sector

Marshall J. Basson, Eric Biddulph-West, Caitlyn Holl, Will Lankenau, Facundo Martin Lopez, Bianca Rose Lott, Chihui Shao, Danny P. Shope, Jay D. Tasson, and Zhiyu Zhang

Phys. Rev. Lett. 137, 081601 (2026) - Published 17 August, 2026

All 43 previously unconstrained Lorentz-violating degrees of freedom in the minimal matter sector are constrained for the first time, completing a decades-long program.

Holographic Origin of a Maximization and Higher-Derivative AdS5/CFT4

Kiril Hristov, Saurish Khandelwal, Yi Pang, and Gabriele Tartaglino-Mazzucchelli

Phys. Rev. Lett. 137, 081602 (2026) - Published 18 August, 2026

Beyond Hagedorn: A Harmonic Approach to TT¯ Deformation

Jie Gu, Jue Hou, and Yunfeng Jiang

Phys. Rev. Lett. 137, 081603 (2026) - Published 21 August, 2026

Toward First Detection of the Solar Mikheyev-Smirnov-Wolfenstein Transition with JUNO

Obada Nairat, John F. Beacom, Kevin J. Kelly, and Shirley Weishi Li

Phys. Rev. Lett. 137, 081801 (2026) - Published 19 August, 2026

First Measurement of the Decay-Time-Integrated CP Asymmetry in Bs0Dsπ+ Decays

R. Aaij et al. (LHCb Collaboration)

Phys. Rev. Lett. 137, 081802 (2026) - Published 21 August, 2026

Four-Loop Gluon Anomalous Dimension of General Lorentz Spin: Transcendental Part

B. A. Kniehl, S.-O. Moch, V. N. Velizhanin, and A. Vogt

Phys. Rev. Lett. 137, 081901 (2026) - Published 17 August, 2026

Next-to-Next-to-Leading-Order QCD Corrections to Hadron Production in Deep-Inelastic Scattering at Finite Transverse Momentum

Liang Dong, Shen Fang, Jun Gao, Hai Tao Li, Ding Yu Shao, and Yu Jiao Zhu

Phys. Rev. Lett. 137, 081902 (2026) - Published 21 August, 2026

Nuclear Physics

Evidence of Nuclear Geometry-Driven Anisotropic Flow in O+O and Ne+Ne Collisions at sNN=5.36TeV

I. J. Abualrob et al. (ALICE Collaboration)

Phys. Rev. Lett. 137, 082301 (2026) - Published 17 August, 2026

Light-ion collisions at the LHC reveal collective hydrodynamic flow with a larger elliptic flow in central Ne-Ne collisions than in OO collisions that might be due to the bowling-pin nuclear shape of 20Ne.

Observation of Long-Range Collective Flow in O+O and Ne+Ne Collisions and Implications for Nuclear Structure Studies

A. Hayrapetyan et al. (CMS Collaboration)

Phys. Rev. Lett. 137, 082302 (2026) - Published 17 August, 2026

Light-ion collisions at the LHC reveal collective hydrodynamic flow with a larger elliptic flow in central Ne-Ne collisions than in OO collisions that might be due to the bowling-pin nuclear shape of 20Ne.

Adiabatic Hydrodynamization and Quasinormal Modes of Nonthermal Attractors

Matisse De Lescluze, Michal P. Heller, Aleksas Mazeliauskas, Bruno Scheihing-Hitschfeld, and Clemens Werthmann

Phys. Rev. Lett. 137, 082303 (2026) - Published 21 August, 2026

Deformation and Magicity in Heavy Actinides: First Observation of the Ground-State Rotational Band of Fm252

R. Orlandi et al.

Phys. Rev. Lett. 137, 082501 (2026) - Published 17 August, 2026

Observation of the ground-state rotational band in 252Fm provides compelling evidence that Z=100 and N=152 act as a deformed doubly magic shell closure.

First Nb94(n,γ) Measurement: Constraining the Nucleosynthetic Origin of Mo94 in Presolar Grains

J. Balibrea-Correa et al. (n_TOF Collaboration)

Phys. Rev. Lett. 137, 082701 (2026) - Published 18 August, 2026

Atomic, Molecular, and Optical Physics

Non-Hermitian Anomalous Scaling Engineering

Shulin Wang, Jiawei He, Zhiyuan Yang, Stefano Longhi, and Peng Xue

Phys. Rev. Lett. 137, 083801 (2026) - Published 18 August, 2026

Physics of Fluids, Earth & Planetary Science, and Climate

Evidence for Wave Turbulence Spectra in Rotating Turbulence

Omri Shaltiel, Omri Gat, and Eran Sharon

Phys. Rev. Lett. 137, 084001 (2026) - Published 18 August, 2026

Evaporative Flux Reversal of Binary Droplets: From Edge to Apex

Minhyeok Kuk and Hyoungsoo Kim

Phys. Rev. Lett. 137, 084002 (2026) - Published 20 August, 2026

Experimental studies of multicomponent droplet evaporation reveal distinct stages, with internal flow shifting from multiple vortices within the droplet to a single toroidal vortex dominating the flow dynamic, departing from the classical single-component picture.

Condensed Matter and Materials

Robust Two-Dimensional Surface Superconductivity and Vortex Lattice in the Weyl Semimetal γPtBi2

Jose Antonio Moreno, Pablo García Talavera, Edwin Herrera, Sara López Valle, Zhuoqi Li, Lin-Lin Wang, Sergey Bud’ko, Alexander I. Buzdin, Isabel Guillamón, Paul C. Canfield, and Hermann Suderow

Phys. Rev. Lett. 137, 086001 (2026) - Published 17 August, 2026

Vortex formation from surface superconductivity is observed in the topological semimetal γ-PtBi2, which confirms the robustness of the surface superconductivity at a higher Tc than the bulk.

Signature of Chiral Superconducting Order Parameter Evidenced in Mesoscopic Superconductors

Xiaoying Xu, Wei Qin, Yuelin Shen, Zixuan Huang, Zhuoya Zhou, Zirao Wang, and Yufan Li

Phys. Rev. Lett. 137, 086002 (2026) - Published 18 August, 2026

Multiple Phases in K2Cr3As3: A Playground for Manipulating Topological Superconductivity

Seigo Ogawa, Tomoki Miyoshi, Saki Uchida, Kazuaki Matano, Shinji Kawasaki, Yoshihiko Inada, and Guo-qing Zheng

Phys. Rev. Lett. 137, 086003 (2026) - Published 19 August, 2026

Researchers have made the first definitive measurements of an elusive superconducting state.

Heterostructuring as Gateway to Electron Doping of Nickelate Superconductors

Chao Deng, Motoharu Kitatani, Guiwen Jiang, Siqi Guo, Niklas Witt, Ao Zhang, Wenfeng Wu, Mi Jiang, Karsten Held, and Liang Si

Phys. Rev. Lett. 137, 086004 (2026) - Published 20 August, 2026

Intercalation-driven self-doping is a general mechanism for engineering high-temperature superconductivity and emergent quantum states in Ruddlesden–Popper phase correlated oxides.

Unlocking Static Polarization and Strain Density Waves in Perovskites by Softening a Hidden Antiferrodistortive Tilt Gradient Mode

Yajun Zhang, Devesh R. Kripalani, Xu He, Konstantin Shapovalov, Jiyuan Yang, Hongjian Zhao, Shi Liu, Huadong Yong, Xingyi Zhang, Jie Wang, Kun Zhou, and Philippe Ghosez

Phys. Rev. Lett. 137, 086101 (2026) - Published 18 August, 2026

Quantized Spin Hall Effect in Three-Dimensional Nodal-Ring Semimetal: Geometric Scaling and Symmetry-Engineered Spin Response

Jiali Chen, Chaoxi Cui, Zhi-Ming Yu, Wei Jiang, and Yugui Yao

Phys. Rev. Lett. 137, 086301 (2026) - Published 17 August, 2026

Anomalous Hydrodynamic Fluctuations in the Quantum XXZ Spin Chain

Takato Yoshimura, Žiga Krajnik, Alvise Bastianello, and Enej Ilievski

Phys. Rev. Lett. 137, 086302 (2026) - Published 17 August, 2026

Discovery of Berezinskii-Kosterlitz-Thouless Correlations in the Quantum Kagome Compound Cs2Cu3SnF12

M. S. Grbić, I. Jakovac, I. Kupčić, H. Tanaka, and M. Horvatić

Phys. Rev. Lett. 137, 086501 (2026) - Published 18 August, 2026

Spin Stripes and Superconductivity in Bilayer Nickelates

Hao-Xin Wang, Hanbit Oh, Tobias Helbig, Bai Yang Wang, Jiarui Li, Yijun Yu, Harold Y. Hwang, Hong-Chen Jiang, Yi-Ming Wu, and S. Raghu

Phys. Rev. Lett. 137, 086502 (2026) - Published 18 August, 2026

Density matrix renormalization group calculations reveal spin-stripe ordering at large Hund’s coupling, demonstrating that Hund’s coupling and inter-layer coupling are key parameters in magnetic order and pairing.

Probing the Quantum Geometry of Correlated Metals Using Optical Conductivity

Deven P. Carmichael and Martin Claassen

Phys. Rev. Lett. 137, 086503 (2026) - Published 18 August, 2026

Majorana Edge Modes in Isolated Wires

Jaden Thomas-Markarian, Kartiek Agarwal, and Ivar Martin

Phys. Rev. Lett. 137, 086504 (2026) - Published 18 August, 2026

Self-Dual Higgs Transitions: Toric Code and Beyond

Wenjie Ji (纪文杰), Ryan A. Lanzetta, Zheng Zhou (周正), and Chong Wang (王翀)

Phys. Rev. Lett. 137, 086505 (2026) - Published 20 August, 2026

Quantized Chern-Simons Axion Coupling in Anomalous Floquet Systems

Lucila Peralta Gavensky, Nathan Goldman, and Gonzalo Usaj

Phys. Rev. Lett. 137, 086601 (2026) - Published 17 August, 2026

Lattice Deformation Induced Higher-Order Hybrid Topology

Peng Wu, Yu-Gui Peng, Qi-Li Sun, Min-Hang Ling, Weiyin Deng, Xue-Feng Zhu, and Zhengyou Liu

Phys. Rev. Lett. 137, 086602 (2026) - Published 17 August, 2026

Quantum Entanglement of XY-Type Spin Dimers on the Shastry-Sutherland Lattice

Qianli Ma, Brianna R. Billingsley, Alin Niraula, Madalynn Marshall, David A. Dahlbom, Yiqing Hao, Daniel M. Pajerowski, Alexander I. Kolesnikov, Xiaojian Bai, Cristian D. Batista, Tai Kong, and Huibo Cao

Phys. Rev. Lett. 137, 086701 (2026) - Published 17 August, 2026

Spinon Singlet Pairing: Origin of d-Wave Sign Structure in a Partially Filled Stripe

Jia-Long Wang, Shi-Jie Hu, and Xue-Feng Zhang

Phys. Rev. Lett. 137, 086702 (2026) - Published 21 August, 2026

Room-Temperature Noncollinear Ferroelectricity in van der Waals WO2Cl2 with a Wide Bandgap

Yu Xing, Ning Ding, Zhipeng Wang, Zhiwen Pan, Lei Guo, Guowei Du, Yangrui Liu, Xiaoxing Cao, Ran Su, Mengting Jiang, Xuezhi Ma, Xiyu Chen, Junchao Zhang, Xinyu Yang, Haoran Ye, Honghong Yao, Rui Feng, Dexiang Chen, Le-Ping Miao, Yumeng You, Zejun Li, Dongsheng Song, Linglong Li, and Shuai Dong

Phys. Rev. Lett. 137, 086801 (2026) - Published 21 August, 2026

Exotic noncollinear room-temperature ferroelectricity has now been experimentally realized in 2D WO2Cl2, establishing a polar counterpart to noncollinear spin textures.

Twin-Twisted van der Waals Crystal for Entangled Photon Source

Chaojie Ma, Mingkang Zhang, Lu He, Yijun Wang, Xuping Shi, Chang Liu, Youbao Ni, Haixin Wu, Yun-Kun Wu, Xifeng Ren, Zhipei Sun, Ling-Jun Kong, Xiangdong Zhang, Hao Hong, and Kaihui Liu

Phys. Rev. Lett. 137, 086901 (2026) - Published 20 August, 2026

Statistical Physics; Classical, Nonlinear, and Complex Systems

Quantum Brownian Motion: Proving that the Schmid Transition Belongs to the Berezinskii-Kosterlitz-Thouless Universality Class

F. G. Capone, A. de Candia, V. Cataudella, R. Fazio, N. Nagaosa, C. A. Perroni, and G. De Filippis

Phys. Rev. Lett. 137, 087101 (2026) - Published 18 August, 2026

Polymers, Chemical Physics, Soft Matter, and Biological Physics

Charged Excitations Made Neutral: N-Centered Ensemble Density Functional Theory of Fukui Functions

Lucien Dupuy and Emmanuel Fromager

Phys. Rev. Lett. 137, 088001 (2026) - Published 18 August, 2026

Curved Odd Elasticity

Yuan Zhou, Lazaros Tsaloukidis, Jack Binysh, Yuchao Chen, Nikta Fakhri, Corentin Coulais, and Piotr Surówka

Phys. Rev. Lett. 137, 088301 (2026) - Published 17 August, 2026

Breakup of an Active Chiral Fluid

Luke Neville, Jens Eggers, and Tanniemola B. Liverpool

Phys. Rev. Lett. 137, 088302 (2026) - Published 19 August, 2026

Paradoxical Increase of Capacity due to Spurious Overlaps in Attractor Networks

Marco Benedetti, Nicolas Brunel, Enzo Marinari, and Ulises Pereira-Obilinovic

Phys. Rev. Lett. 137, 088401 (2026) - Published 18 August, 2026

Quantitative and Predictive Folding Models from Limited Single-Molecule Data Using Simulation-Based Inference

Lars Dingeldein, Aaron Lyons, Pilar Cossio, Michael T. Woodside, and Roberto Covino

Phys. Rev. Lett. 137, 088402 (2026) - Published 19 August, 2026

A simulation-based inference framework combines physics-based modeling with deep learning to recover the Bayesian posterior of a biomolecular folding model directly from single-molecule force spectroscopy data.

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