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Electrophoresis of a DNA coil near a nanopore
Phys. Rev. E 87, 042723 – Published 29 April, 2013
DOI: https://doi.org/10.1103/PhysRevE.87.042723
Abstract
Motivated by DNA electrophoresis near a nanopore, we consider the flow field around an “elongated jet,” a long thin source which injects momentum into a liquid. This solution qualitatively describes the electro-osmotic flow around a long rigid polymer, where due to electrohydrodynamic coupling, the solvent receives momentum from the electric field. Based on the qualitative behavior of the elongated jet solution, we develop a coarse-grained scheme which reproduces the known theoretical results regarding the electrophoretic behavior of a long rigid polymer and a polymer coil in a uniform field, which we then exploit to analyze the electrophoresis of a polymer coil in the nonuniform field near a nanopore.
Article Text
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