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Evolutionary processes in finite populations

Dirk M. Lorenz1, Jeong-Man Park1,2, and Michael W. Deem1,3

  • 1Department of Physics, Rice University, Houston, Texas
  • 2Department of Physics, The Catholic University of Korea, Bucheon, Korea
  • 3Department of Bioengineering, Rice University, Houston, Texas

Phys. Rev. E 87, 022704 – Published 13 February, 2013

DOI: https://doi.org/10.1103/PhysRevE.87.022704

Abstract

We consider the evolution of large but finite populations on arbitrary fitness landscapes. We describe the evolutionary process by a Markov-Moran process. We show that to O(1/N), the time-averaged fitness is lower for the finite population than it is for the infinite population. We also show that fluctuations in the number of individuals for a given genotype can be proportional to a power of the inverse of the mutation rate. Finally, we show that the probability for the system to take a given path through the fitness landscape can be nonmonotonic in system size.

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