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Free-energy barrier for electric-field-driven polymer entry into nanoscale channels

Narges Nikoofard1 and Hossein Fazli1,2,*

  • 1Department of Physics, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran
  • 2Department of Biological Sciences, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan 45137-66731, Iran

  • *fazli@iasbs.ac.ir
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Phys. Rev. E 83, 050801(R) – Published 26 May, 2011

DOI: https://doi.org/10.1103/PhysRevE.83.050801

Abstract

Free-energy barrier for entry of a charged polymer into a nanoscale channel by a driving electric field is studied theoretically and using molecular dynamics simulations. Dependence of the barrier height on the polymer length, the driving field strength, and the channel entrance geometry is investigated. Squeezing effect of the electric field on the polymer before its entry to the channel is taken into account. It is shown that lateral confinement of the polymer prior to its entry changes the polymer length dependence of the barrier height noticeably. Our theory and simulation results are in good agreement and reasonably describe related experimental data.

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      Phys. Rev. E 83, 050801(R)– Published 26 May, 2011
      • Received 11 January 2011

      © 2011 American Physical Society

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