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Anomalous drift of spiral waves in heterogeneous excitable media

S. Sridhar1, Sitabhra Sinha1, and Alexander V. Panfilov2

  • 1The Institute of Mathematical Sciences, CIT Campus, Taramani, Chennai 600113, India
  • 2Department of Theoretical Biology, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands

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Phys. Rev. E 82, 051908 – Published 4 November, 2010

DOI: https://doi.org/10.1103/PhysRevE.82.051908

Abstract

We study the drift of spiral waves in a simple model of heterogeneous excitable medium, having gradients in the distribution of ion-channel expression or cellular coupling. We report the anomalous drift of spiral waves toward regions having shorter period or stronger coupling, in reaction-diffusion models of excitable media. Such anomalous drift can promote the onset of complex spatiotemporal patterns, e.g., those responsible for life-threatening arrhythmias in the heart.

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Phys. Rev. E 82, 051908– Published 4 November, 2010
  • Received 29 September 2009

© 2010 American Physical Society

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