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Biopolymer network geometries: Characterization, regeneration, and elastic properties

Stefan B. Lindström1,*, David A. Vader2, Artem Kulachenko3, and David A. Weitz2,†

  • 1Department of Fiber and Polymer Technology, Royal Institute of Technology, SE-100 44 Stockholm, Sweden
  • 2School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA
  • 3Department of Solid Mechanics, Royal Institute of Technology, SE-100 44 Stockholm, Sweden

  • *stefan.lindstroem@gmail.com
  • †weitz@seas.harvard.edu
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Phys. Rev. E 82, 051905 – Published 3 November, 2010

DOI: https://doi.org/10.1103/PhysRevE.82.051905

Abstract

We study the geometry of biopolymer networks and effects of the geometry on bulk mechanical properties. It is shown numerically that the physical network geometry can be quantified statistically and regenerated from its statistical description, so that the regenerated network exhibits the same network mechanics as the physical network in the elastic regime. A collagen-I biopolymer network is used for validation. The method enables parametric studies of the network geometry, whose parameters are often difficult to vary independently in experiments.

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Phys. Rev. E 82, 051905– Published 3 November, 2010
  • Received 3 June 2010

© 2010 American Physical Society

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