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Characteristics of temporal fluctuations in the hyperpolarized state of the cortical slow oscillation

M. T. Wilson1,*, M. Barry2, J. N. J. Reynolds2, E. J. W. Hutchison1, and D. A. Steyn-Ross1

  • 1Department of Engineering, University of Waikato, Private Bag 3105, Hamilton 3240, New Zealand
  • 2Department of Anatomy and Structural Biology, University of Otago School of Medical Sciences, P.O. Box 913, Dunedin 9016, New Zealand

  • *m.wilson@waikato.ac.nz
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Phys. Rev. E 77, 061908 – Published 11 June, 2008

DOI: https://doi.org/10.1103/PhysRevE.77.061908

Abstract

We present evidence for the hypothesis that transitions between the low- and high-firing states of the cortical slow oscillation correspond to neuronal phase transitions. By analyzing intracellular recordings of the membrane potential during the cortical slow oscillation in rats, we quantify the temporal fluctuations in power and the frequency centroid of the power spectrum in the period of time before “down” to “up” transitions. By taking appropriate averages over such events, we present these statistics as a function of time before transition. The results demonstrate an increase in fluctuation power and time scale broadly consistent with the slowing of systems close to phase transitions. The analysis is complicated and limited by the difficulty in identifying when transitions begin, and removing dc trends in membrane potential.

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Phys. Rev. E 77, 061908– Published 11 June, 2008
  • Received 24 September 2007

© 2008 American Physical Society

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