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Relaxation dynamics of a single DNA molecule

E. Goshen1, W. Z. Zhao1,3, G. Carmon1, S. Rosen1, R. Granek2, and M. Feingold1

  • 1Department of Physics and The Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105, Israel
  • 2Department of Biotechnology Engineering and Institute for Applied Biosciences, Ben Gurion University, Beer Sheva 84105, Israel
  • 3Department of Mathematics, Capital Normal University, Beijing 100037, China

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Phys. Rev. E 71, 061920 – Published 28 June, 2005

DOI: https://doi.org/10.1103/PhysRevE.71.061920

Abstract

The relaxation of a single DNA molecule is studied. The experimental system consists of optical tweezers and a micron-sized bead that is tethered to the bottom of the sample by a single double-stranded DNA molecule. The bead slows down the DNA relaxation from a strongly stretched configuration such that it is passing through stretched equilibrium states. This allows for a theoretical description of the relaxation trajectory, which is in good agreement with experiment.

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Phys. Rev. E 71, 061920– Published 28 June, 2005
  • Received 3 February 2005

© 2005 American Physical Society

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