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Molecular motions in lipid bilayers studied by the neutron backscattering technique

Maikel C. Rheinstädter*, Tilo Seydel, and Franz Demmel

Tim Salditt

  • Institut Laue-Langevin, 6 rue Jules Horowitz, BP 156, 38042 Grenoble Cedex 9, France

  • Institut für Röntgenphysik, Georg-August-Universität Göttingen, Geiststrasse 11, 37037 Göttingen, Germany

  • *Electronic address: rheinstaedter@ill.fr
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Phys. Rev. E 71, 061908 – Published 20 June, 2005

DOI: https://doi.org/10.1103/PhysRevE.71.061908

Abstract

We report a high energy-resolution neutron backscattering study to investigate slow motions on nanosecond time scales in highly oriented solid supported phospholipid bilayers of the model system DMPC-d54 (deuterated 1,2-dimyristoyl-sn-glycero-3-phoshatidylcholine), hydrated with heavy water. This technique allows to discriminate the onset of mobility at different length scales for the different molecular components, as, e.g., the lipid acyl-chains and the hydration water in between the membrane stacks, respectively, and provides a benchmark test regarding the feasibility of neutron backscattering investigations on these sample systems. We discuss freezing of the lipid acyl-chains, as observed by this technique, and observe a second freezing transition which we attribute to the hydration water.

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Phys. Rev. E 71, 061908– Published 20 June, 2005
  • Received 31 January 2005

© 2005 American Physical Society

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