Export citation

Export citation

Choose format for download:

Download Citation
  • Access by Xinjiang University

Magnetic resonance force microscopy

J. A. Sidles, J. L. Garbini, K. J. Bruland, D. Rugar, O. Züger, S. Hoen, and C. S. Yannoni

J. A. Sidles

  • Department of Orthopaedics, School of Medicine, University of Washington, Seattle, Washington 98195

J. L. Garbini and K. J. Bruland

  • Department of Mechanical Engineering, University of Washington, Seattle, Washington 98195

D. Rugar, O. Züger, S. Hoen, and C. S. Yannoni

  • IBM Research Division, Almaden Research Center, 650 Harry Road, San Jose, California 95120

Rev. Mod. Phys. 67, 249 – Published 1 January, 1995

DOI: https://doi.org/10.1103/RevModPhys.67.249

Abstract

Recent initial experiments in magnetic resonance force microscopy (MRFM) have detected the magnetic force exerted by electrons and nuclei in microscopic samples. The experiments generate a force signal by modulating the sample magnetization with standard magnetic resonance techniques. Sample sizes of a few nanograms generate readily detected force signals of order 1014 to 1016 Newtons. This article describes the present status of MRFM technology, with particular attention to the feasibility of detecting single-electron magnetic moments, and the possible applications of MRFM in biological imaging.

References (105)

  1. Abragam, A., 1961, Principles of Nuclear Magnetism (Clarendon, Oxford), pp. 86 and 548
  2. Alberts, B., D. Bray, J. Lewis, M. Raff, K. Roberts, and J. D. Watson, 1994, Molecular Biology of the Cell, third edition (Garland, New York), pp. 148 and 155
  3. Albrecht, T. R., D. Grütter, D. Horne, and D. Rugar, 1991, J. Appl. Phys. 69, 668-673
  4. Amrein, M., R. Durr, A. Stasiak, H. Gross, and G. Travaglini, 1989, Science 243, 1708-1711
  5. Bartunik, H. D., L. J. Bartunik, and H. Viehmann, 1992, Philos. Trans. R. Soc. Lond. A 340, 209-220
  6. Bernstein, F. C., T. F. Koetzle, G. J. B. Williams, E. F. Meyer Jr., M. D. Brice, J. R. Rodgers, O. Kennard, T. Shimanouchi, and M. Tasumi, 1977, J. Mol. Biol. 112, 535-542
  7. Berry, B. S., and A. S. Nowick, 1966, in Physical Acoustics Vol. IIIA, edited by W. P. Mason (Academic, New York), pp. 1-42
  8. Binh, V. T., N. Garcia, and A. L. Levanuyk, 1994, Surf. Sci. Lett. 301, L224-L228
  9. Binnig, G., H. Rohrer, C. Gerber, and E. Weibel, 1982a, Appl. Phys. Lett. 40, 178-180
  10. Binnig, G., H. Rohrer, C. Gerber, and E. Weibel, 1982b, Phys. Rev. Lett. 49, 57-60
  11. Binnig, G., H. Rohrer, C. Gerber, and E. Weibel, 1983, Phys. Rev. Lett. 50, 120-123
  12. Binnig, G., C. F. Quate, and C. Gerber, 1986, Phys. Rev. Lett. 56, 930-933
  13. Blair, D. G., 1991, in The Detection of Gravitational Waves, edited by D. G. Blair (Cambridge University Press, Cambridge, England), pp. 73-98
  14. Bloom, M., 1993, in Nuclear Magnetic Double Resonance, Proceedings of the International School of Physics "Enrico Fermi", edited by B. Maraviglia (North Holland, Amsterdam), pp. 473-484
  15. Brown, L. S., and G. Gabrielse, 1986, Rev. Mod. Phys. 58, 233-312
  16. Bruines, J. J. P., V. J. de Waal, and J. E. Mooj, 1982, J. Low Temp. Phys. 46, 383-396
  17. Buser, R. A., and N. F. de Rooij, 1990, Sens. Actuators A 21-23, 323-327
  18. Caves, C. M., 1980, Phys. Rev. Lett. 45, 75-79
  19. Caves, C. M., 1981, Phys. Rev. D 23, 1693-1708
  20. Chen, G. Y., R. J. Warmack, T. Thundat, D. P. Allison, and A. Haug, 1994, Rev. Sci. Instrum. 65, 2532-2537
  21. Cho, Y., S. Gorina, P. D. Jeffrey, and N. P. Pavletich, 1994, Science 265, 346-355
  22. Clarke, J., 1990, in Superconducting Devices, edited by S. T. Ruggiero and D. A. Rudman (Academic, New York), pp. 51-101
  23. Clore, G. M., J. G. Omichinski, K. Sakaguchi, N. Zambrano, H. Sakamoto, E. Appella, and A. M. Groneborn, 1994, Science 265, 386-391
  24. Cory, D. G., 1992, in Annual Reports on NMR Spectroscopy, edited by G. A. Webb (Academic, London), pp. 87-180
  25. Dahm, A. J., A. Denenstein, D. N. Langenberg, W. H. Parker, D. Rogovin, and D. J. Scalapino, 1969, Phys. Rev. Lett. 22, 1416-1420
  26. Darnell, J. E., H. Lodish, and D. Baltimore, 1990, Molecular Cell Biology, third edition (Scientific American Books, New York)
  27. Dehmelt, H., 1988, Z. Phys. D 10, 127-134
  28. Dehmelt, H., 1990, Rev. Mod. Phys. 62, 525-530
  29. de Waal, V. J., P. Schrijner, and R. Llurba, 1984, J. Low Temp. Phys. 54, 215-232
  30. Drake, B., C. B. Prater, A. L. Weisenhorn, S. A. C. Gould, T. R. Albrecht, C. F. Quate, D. S. Cannell, H. G. Hansma, and P. K. Hansma, 1989, Science 243, 1586-1589
  31. Driscoll, R. J., M. G. Youngquist, and J. D. Baldeschwieler, 1990, Nature 346, 294-296
  32. Edelstein, W. A., J. Hough, J. R. Pugh, and W. Martin, 1978, J. Phys. E 11, 710-712
  33. Edstam, J., and H. K. Olsson, 1992, in Superconducting Devices and Applications, Springer Proceedings in Physics Vol. 64, edited by H. Koch and H. Lübbig (Springer, Berlin), pp. 224-227
  34. Ferreirinho, J., 1991, in The Detection of Gravitational Waves, edited by D. G. Blair (Cambridge University, Cambridge), pp. 116-168
  35. Fraser, D. B., 1968, in Physical Acoustics Vol. V, edited by W. P. Mason (Academic, New York), pp. 59-110
  36. Friend, S., 1994, Science 265, 334-335
  37. Garstens, M. A., and J. I. Kaplan, 1955, Phys. Rev. 99, 459-463
  38. Gibson, G. A., and S. Schultz, 1991, J. Appl. Phys. 69, 5880-5882
  39. Gould, S. A. C., B. Drake, C. B. Prater, A. L. Weisenhorn, S. Manne, G. L. Kelderman, H. J. Butt, H. Hansma, P. K. Hansma, S. Magonov, and H. J. Cantow, 1990, Ultramicroscopy 33, 93-98
  40. Granato, A. V., and K. Lucke, 1966, in Physical Acoustics Vol. IVA, edited by W. P. Mason (Academic, New York), pp. 225-276
  41. Hansma, H. G., R. L. Sinsheimer, J. Groppe, T. C. Bruice, V. Elings, G. Gurley, M. Bezanilla, I. A. Mastrangelo, P. V. C. Hough, and P. K. Hansma, 1993, Scanning 15, 296-299
  42. Hansma, H. G., A. L. Weisenhorn, S. A. C. Gould, R. L. Sinsheimer, H. E. Gaub, G. D. Stucky, C. M. Zaremba, and P. K. Hansma, 1991, J. Vac. Sci. Technol. B 9, 1282-1284
  43. Harris, C. C., 1994, Science 262, 1980-1981
  44. Hobbs, P., D. Abraham, and H. Wickramasinghe, 1989, Appl. Phys. Lett. 55, 2357-2359
  45. Hoen, S., O. Züger, C. S. Yannoni, H. J. Mamin, K. Wago, and D. Rugar, 1994, in Technical Digest of the 1994 Solid State Sensor and Actuator Workshop, Hilton Head, SC (Transducers Research Foundation, Catalog No. 94TRF-0001), pp. 209-212
  46. Jaklevic, R. C., J. Lambe, A. H. Silver, and J. E. Mercereau, 1964, Phys. Rev. Lett. 12, 159-160
  47. Kent, A. D., T. M. Shaw, S. von Molnar, and D. D. Awschalom, 1993, Science 262, 1249-1252
  48. Ketchen, M. B., 1992, Springer Proceedings in Physics Vol. 64, edited by H. Koch and H. Lübbig (Springer, New York), pp. 256-264
  49. Ketchen, M. B., D. D. Awschalom, W. J. Gallagher, A. W. Kleinsasser, R. L. Sandstrom, J. R. Rozen, and B. Bumble, 1989, IEEE Trans. Magn. 25, 1212-1215
  50. Ketchen, M., D. J. Pearson, K. Stawiasz, C. K. Hu, A. W. Kleinsasser, T. Brunner, C. Cabral, V. Chandrashekhar, M. Jaso, M. Manny, and K. Stein, 1993, IEEE Trans. Appl. Supercond. 3, 1795-1799
  51. Klemens, P. G., 1966, in Physical Acoustics Vol. IIIB, edited by W. P. Mason (Academic, New York), pp. 201-234
  52. Koch, R. H., D. J. Van Harlingen, and J. Clarke, 1980, Phys. Rev. Lett. 45, 2132-2135
  53. Koch, R. H., D. J. Van Harlingen, and J. Clarke, 1981a, Appl. Phys. Lett. 38, 380-382
  54. Koch, R. H., D. J. Van Harlingen, and J. Clarke, 1981b, Phys. Rev. Lett. 47, 1216-1219
  55. Lal, R., and S. A. John, 1993, Am. J. Physiol. 226, C1-C21
  56. Langdon, R. M., and D. L. Dowe, 1987, Fiber Optic Sensors II, SPIE 798, 86-93
  57. Lauterbur, P. C., 1973, Nature 242, 190-191
  58. Likharev, K. K., 1990, in Superconducting Devices, edited by S. T. Ruggiero and D. A. Rudman (Academic, New York), pp. 1-50
  59. Mamin, H. J., D. Rugar, J. E. Stern, R. E. Fontana Jr., and P. Kasiraj, 1989, Appl. Phys. Lett. 55, 318-320
  60. Mansfield, P., and P. G. Morris, 1982, NMR Imaging in Biomedicine (Academic, New York)
  61. Martin, Y., and H. K. Wickramasinghe, 1987, Appl. Phys. Lett. 50, 1455-1457
  62. Mason, W. P., 1942, Electromechanical Transducers and Wave Filters (Van Nostrand, New York), p. 90
  63. Mason, W. P., 1966, in Physical Acoustics Vol. IIIB, edited by W. P. Mason (Academic, New York), pp. 235-286
  64. Mastrangelo, I. A., M. Bezanilla, P. K. Hansma, P. V. C. Hough, and H. G. Hansma, 1994, Biophys. J. 66, 293-296
  65. Morrow, C. D., J. Part, and J. K. Wakefield, 1994, Am. J. Physiol. 266, C1135-C1156
  66. Morse, P. M., 1936, Vibration and Sound (McGraw-Hill, New York), pp. 119-120
  67. Neumeister, J. M., and W. A. Ducker, 1994, Rev. Sci. Instrum. 65, 2527-2531
  68. Pace, A. F., M. J. Collett, and D. F. Walls, 1993, Phys. Rev. A 47, 3173-3189
  69. Pitcher, R. J., K. W. H. Foulds, J. A. Clements, and J. M. Naden, 1990, Sens. Actuators A 21-23, 387-390
  70. Ramsey, N., 1956, Molecular Beams (Clarendon, Oxford)
  71. Randall, R. H., F. C. Rose, and C. Zener, 1939, Phys. Rev. 56, 343-348
  72. Rees, W. A., R. W. Keller, J. P. Vesenka, G. Yang, and C. Bustamante, 1993, Science 260, 1646-1649
  73. Roberts, R. L., R. G. Kessel, and H. Tung, 1991, Freeze Fracture Images of Cells and Tissues (Oxford University, Oxford)
  74. Robinson, B. H., D. A. Haas, and C. Mailer, 1994, Science 263, 490-493
  75. Robinson, B., H. Thomann, A. H. Beth, P. Fajer, and L. Dalton, 1985a, in EPR and Advanced EPR Studies of Biological Systems, edited by L. R. Dalton (CRC, Boca Raton), pp. 12-108
  76. Robinson, B., H. Thomann, A. H. Beth, P. Fajer, and L. Dalton, 1985b, in EPR and Advanced EPR Studies of Biological Systems, edited by L. R. Dalton (CRC, Boca Raton), pp. 296-301
  77. Roszhart, T. V., 1990, in IEEE Sensor and Actuator Workshop (IEEE, Hilton Head Island, SC), pp. 13-16
  78. Rugar, D., and P. Grütter, 1991, Phys. Rev. Lett. 67, 699-702
  79. Rugar, D., and P. Hansma, 1990, Physics Today 43 (October), 23-30
  80. Rugar, D., H. J. Mamin, and P. Guethner, 1989, Appl. Phys. Lett. 55, 2588-2590
  81. Rugar, D., C. S. Yannoni, and J. A. Sidles, 1992, Nature 360, 563-566
  82. Rugar, D., O. Züger, S. Hoen, C. S. Yannoni, H. M. Vieth, and R. D. Kendrick, 1994, Science 264, 1560-1563
  83. Sáenz, J. J., N. Garcia, P. Grütter, E. Meyer, H. Heinzelmann, R. Weisendanger, L. Rosenthaler, H. R. Hidber, and H. J. Gütherodt, 1987, J. Appl. Phys. 62, 4293-4295
  84. Sidles, J. A., 1991, Appl. Phys. Lett. 58, 2854-2856
  85. Sidles, J. A., 1992, Phys. Rev. Lett. 68, 1124-1127
  86. Sidles, J. A., J. L. Garbini, and G. P. Drobny, 1992, Rev. Sci. Instrum. 63, 3881-3899
  87. Sidles, J. A., and D. Rugar, 1993, Phys. Rev. Lett. 70, 3506-3509
  88. Slichter, C. P., 1989, Principles of Magnetic Resonance, third edition (Springer, New York)
  89. Smythe, W. R., 1968, Static and Dynamic Electricity, third edition (McGraw-Hill, New York), pp. 339-340
  90. Stephen, M. J., 1968, Phys. Rev. Lett. 21, 1629-1632
  91. Stuart, D., 1994, Nature 371, 19
  92. Tesche, C. D., and J. Clarke, 1977, J. Low Temp. Phys. 29, 301-331
  93. Weisenhorn, A. L., B. Drake, C. B. Prater, S. A. C. Gould, P. K. Hansma, F. Ohnesorge, M. Egger, S. P. Heyn, and H. E. Gaub, 1990, Biophys. J. 58, 1251-1258
  94. Whitfield, G., and A. G. Redfield, 1957, Phys. Rev. 106, 918-920
  95. Wilson, J., and T. Hunt, 1994, Molecular Biology of the Cell: The Problems Book (Garland, New York)
  96. Wineland, D. J., P. Ekstrom, and H. G. Dehmelt, 1973, Phys. Rev. Lett. 31, 1279-1282
  97. Wootters, W. K., and W. H. Zurek, 1982, Nature 299, 802-803
  98. Yannoni, C. S., O. Züger, J. A. Sidles, and D. Rugar, 1994, in Encyclopedia for Magnetic Resonance, edited by D. M. Grant and R. K. Harris (John Wiley and Sons Ltd., Sussex), in press
  99. Youngquist, M. G., R. J. Driscoll, T. R. Coley, W. A. Goddard, and J. D. Baldeschwieler, 1991, J. Vac. Sci. Technol. B 9, 1304-1308
  100. Zener, C., 1937, Phys. Rev. 52, 230-235
  101. Zener, C., 1938, Phys. Rev. 53, 90-99
  102. Zhang, L. M., D. Uttamchandani, and B. Culshaw, 1990, Sens. Actuators A 21-23, 391-393
  103. Zook, J. D., D. W. Burns, H. Guckel, J. J. Sniegowski, R. L. Engelstad, and Z. Feng, 1992, Sens. Actuators A 35, 51-59
  104. Züger, O., and D. Rugar, 1993, Appl. Phys. Lett. 63, 2496-2498
  105. Züger, O., and D. Rugar, 1994, J. Appl. Phys. 75, 6211-6216

Outline

Information

Sign In to Your Journals Account

Filter

Filter

Article Lookup

Enter a citation