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Biological magnetometers, driven by mechanisms like radical-pair, magnetite, and MagR, may approach the quantum energy resolution limit, linking magnetic sensitivity to Planck’s constant and guiding advancements in biomimetic sensing technologies.

From the article:

Approaching the Quantum Limit of Energy Resolution in Animal Magnetoreception
I. K. Kominis and E. Gkoudinakis
PRX Life 3, 013004 (2025)

HIGHLIGHTED ARTICLES

Approaching the Quantum Limit of Energy Resolution in Animal Magnetoreception

I. K. Kominis and E. Gkoudinakis

PRX Life 3, 013004 (2025) - Published 16 January, 2025

Biological magnetometers, driven by mechanisms like radical-pair, magnetite, and MagR, may approach the quantum energy resolution limit, linking magnetic sensitivity to Planck’s constant and guiding advancements in biomimetic sensing technologies.

ARTICLES

Hair Cells in the Cochlea Must Tune Resonant Modes to the Edge of Instability without Destabilizing Collective Modes

Asheesh S. Momi, Michael C. Abbott, Julian Rubinfien, Benjamin B. Machta, and Isabella R. Graf

PRX Life 3, 013001 (2025) - Published 2 January, 2025

A generic model of the cochlea supports two distinct types of modes and reveals how activity in individual hair cells collectively creates a critical cochlea.

Spontaneous and Induced Oscillations in Confined Epithelia

Toshi Parmar, Liam P. Dow, Beth L. Pruitt, and M. Cristina Marchetti

PRX Life 3, 013002 (2025) - Published 9 January, 2025

This combined theoretical and experimental study of spontaneous density waves in confined epithelial cell trains highlights the mechanochemical feedback driving oscillations and shaping responses to external forces within size-constrained, one-dimensional tissues.

High Ground State Overlap via Quantum Embedding Methods

Mihael Erakovic, Freek Witteveen, Dylan Harley, Jakob Günther, Moritz Bensberg, Oinam Romesh Meitei, Minsik Cho, Troy Van Voorhis, Markus Reiher, and Matthias Christandl

PRX Life 3, 013003 (2025) - Published 14 January, 2025

Quantum embedding methods mitigate the orthogonality catastrophe problem of initial state preparation in large molecular systems, such as proteins and nucleic acids, paving the way for the use of quantum phase estimation for ground state energy calculations.

Approaching the Quantum Limit of Energy Resolution in Animal Magnetoreception

I. K. Kominis and E. Gkoudinakis

PRX Life 3, 013004 (2025) - Published 16 January, 2025

Biological magnetometers, driven by mechanisms like radical-pair, magnetite, and MagR, may approach the quantum energy resolution limit, linking magnetic sensitivity to Planck’s constant and guiding advancements in biomimetic sensing technologies.

Harnessing Long-Range Temporal Correlations for Advanced Epilepsy Classification

Vadim V. Grubov, Alexander K. Kuc, Semen A. Kurkin, Denis A. Andrikov, Nikita Utyashev, Vladimir A. Maksimenko, Oleg E. Karpov, and Alexander E. Hramov

PRX Life 3, 013005 (2025) - Published 21 January, 2025

Detrended fluctuation analysis reveals altered long-range correlations in epilepsy, enabling machine learning models trained on these features to outperform spectral methods in classifying epileptic responses to intermittent photic stimulation in non-photosensitive epilepsy.

Variability in Protein Expression and Fitness Under Stress: Distinct Modes of Early Adaptation of Populations

Maor Knafo, Shahar Rezenman, Reinat Nevo, Ivgeni Tsigalnitski, Ziv Reich, and Ruti Kapon

PRX Life 3, 013006 (2025) - Published 30 January, 2025

Yeast populations adapt to environmental changes through two distinct modes, determined by stress familiarity: rare stressors trigger uniform adaptation, while familiar ones elicit diverse responses, reflected in gene expression variability.

Bacterial proliferation pattern formation

John S. Chuang, Riccardo Rao, and Stanislas Leibler

PRX Life 3, 013007 (2025) - Published 4 February, 2025

Proliferation of immobilized bacteria subjected to transient nutrient gradients reveals a variety of banded patterns which can be modified through either genetic or chemical environment changes.

Swirling Instability Mediated by Elastic and Hydrodynamic Couplings in Cytoplasmic Streaming

Takuji Ishikawa, Takayuki Torisawa, Hirofumi Wada, and Akatsuki Kimura

PRX Life 3, 013008 (2025) - Published 6 February, 2025

Simulations reveal that reversing cytoplasmic swirls in C. elegans zygotes arise spontaneously from the interplay of endoplasmic reticulum elasticity and hydrodynamic forces, enabling efficient intracellular mixing during embryogenesis.

Mechanistic Insights into Z-Ring Formation and Stability

Rajneesh Kumar, Ramanujam Srinivasan, and Debasish Chaudhuri

PRX Life 3, 013009 (2025) - Published 11 February, 2025

FtsZ filaments form diverse structures, including Z-rings, through dynamic transitions driven by treadmilling and mechanical stresses.

Universal Niche Geometry Governs the Response of Ecosystems to Environmental Perturbations

Akshit Goyal, Jason W. Rocks, and Pankaj Mehta

PRX Life 3, 013010 (2025) - Published 13 February, 2025

Ecosystem responses to perturbations can be predicted introducing a universal geometric framework that maps species-resource interactions onto vector spaces, revaling fundamental limits on inferring ecological interactions from perturbation data.

Conformational Entropy of Intrinsically Disordered Proteins Bars Intruders from Biomolecular Condensates

Vladimir Grigorev, Ned S. Wingreen, and Yaojun Zhang

PRX Life 3, 013011 (2025) - Published 14 February, 2025

Intrinsically disordered regions are gatekeepers of biomolecular condensates, excluding intruder molecules by imposing a size-dependent entropic free-energy barrier.

Confinement, Jamming, and Adhesion in Cancer Cells Dissociating from a Collectively Invading Strand

Wei Wang (汪巍), Robert A. Law, Emiliano Perez Ipiña, Konstantinos Konstantopoulos, and Brian A. Camley

PRX Life 3, 013012 (2025) - Published 25 February, 2025

A phase field model of cancer cell invasion explores how confinement, adhesion, and chemotaxis control whether clumps of cells break off from the invading front, capturing experimental behavior observed in microfluidic channels.

Emergence of a Dynamical State of Coherent Bursting with Power-Law Distributed Avalanches from Collective Stochastic Dynamics of Adaptive Neurons

Lik-Chun Chan, Tsz-Fung Kok, and Emily S. C. Ching

PRX Life 3, 013013 (2025) - Published 4 March, 2025

When there is a balance between strong excitation and negative adaptive feedback, random inputs can drive a network of neurons toward synchronized bursting and power-law avalanches, mirroring patterns observed in the brain.

Loop-Extruder-Mediated Rigidity Can Globally Order Bacterial Chromosomes

Janni Harju, Till Armbruster, and Chase Broedersz

PRX Life 3, 013014 (2025) - Published 7 March, 2025

Motor proteins which create DNA loops can orient the E. coli chromosome and position its left and right arms on opposite sides of the cell without the need for anchoring, as shown in this study using theory and 3D polymer simulations.

DNA Transport is Topologically Sculpted by Active Microtubule Dynamics

Dylan P. McCuskey, Raisa E. Achiriloaie, Claire Benjamin, Jemma Kushen, Isaac Blacklow, Omar Mnfy, Jennifer L. Ross, Rae M. Robertson-Anderson, and Janet Y. Sheung

PRX Life 3, 013015 (2025) - Published 13 March, 2025

By tracking single-molecules, this study shows that circular DNA threads through kinesin-driven microtubule networks, exhibiting enhanced superdiffusion and subdiffusion compared to linear DNA, with DNA topology coupling directed motion and stalling to modulate transport.

Q-BiC: A Biocompatible Integrated Chip for in vitro and in vivo Spin-Based Quantum Sensing

Louise Shanahan, Sophia Belser, Jack W. Hart, Qiushi Gu, Julien R. E. Roth, Annika Mechnich, Michael Högen, Soham Pal, Toby Mitchell, David Jordan, Eric A. Miska, Mete Atatüre, and Helena S. Knowles

PRX Life 3, 013016 (2025) - Published 18 March, 2025

Q-BiC is a platform containing integrated microcircuitry that facilitates non-invasive spin-based quantum sensing inside living cells and organisms, allowing for multimodal real-time data acquisition without affecting biological function.

Rethinking Robust Adaptation: Characterization of Structural Mechanisms for Biochemical Network Robustness through Topological Invariants

Yuji Hirono, Ankit Gupta, and Mustafa Khammash

PRX Life 3, 013017 (2025) - Published 20 March, 2025

A framework uncovering hidden integral control systems reveals a universal topological principle governing biochemical robust perfect adaptation.

Protein Folding as a Jamming Transition

Alex T. Grigas, Zhuoyi Liu, Jack A. Logan, Mark D. Shattuck, and Corey S. O'Hern

PRX Life 3, 013018 (2025) - Published 27 March, 2025

Densely packed protein cores have the same interior packing density irrespective of overall fold, arising from a jamming transition where amino acids reach a critical, incompressible density, as explained by an all-atom polymer model.

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