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TUTORIALS

Denario Project: Deep Knowledge Artificial Intelligence Agents for Scientific Discovery

Francisco Villaescusa-Navarro et al.

PRX Intelligence 1, 021001 (2026) - Published 1 October, 2026

This Tutorial presents Denario, an AI multiagent system that can assist in the full scientific process, and provides examples and guidance for its application.

Machine Learning on Heterogeneous, Edge, and Quantum Hardware for Particle Physics

Julia Gonski et al.

PRX Intelligence 1, 021201 (2026) - Published 13 October, 2026

This Roadmap envisions how to prioritize research in hardware-based machine learning methods and more to adapt to challenging real-time data collection environments in the forthcoming era of particle physics experiments.

ARTICLES

Pareto Frontier of Neural Quantum States: Scalable, Affordable, and Accurate Convolutional Backflow for Strongly Correlated Lattice Fermions

Yuntian Gu, Zeyao Han, Wenrui Li, Zhiyu Xiao, Tao Xiang, Mingpu Qin, Liwei Wang, and Dingshun Lv

PRX Intelligence 1, 023001 (2026) - Published 6 October, 2026

Comprehensive benchmarking demonstrates the power and robustness of two convolutional backflow architectures for strongly correlated systems.

Scientific Machine Learning of Chaotic Systems Learns Reduced-Order Equations for Neural Populations

Anthony G. Chesebro, David Hofmann, Vaibhav Dixit, Earl K. Miller, Richard H. Granger, Alan Edelman, Christopher V. Rackauckas, Lilianne R. Mujica-Parodi, and Helmut H. Strey

PRX Intelligence 1, 023002 (2026) - Published 8 October, 2026

An approach that uses prediction-error methodology to train universal differential equations can learn unknown states in chaotic systems by removing the sensitive dependence of conventional methods on parameter choices.

Sampling Weights at Intermediate Temperatures is Optimal for Training Large Language Protein Models

L. Ghiringhelli, A. Zambon, and G. Tiana

PRX Intelligence 1, 023003 (2026) - Published 14 October, 2026

Transformer models trained for protein structure prediction are analyzed from a statistical mechanics perspective, leading to a better understanding of how they work and why they can efficiently retrieve spatial and chemical relationships between amino acids.

OmniCosmos: Transferring Particle Physics Knowledge Across the Cosmos

Vinicius Mikuni, Ibrahim Elsharkawy, and Benjamin Nachman

PRX Intelligence 1, 023004 (2026) - Published 15 October, 2026

AI Foundation Models trained on collider data can translate to cosmology.

Probabilistic Denoising for Reliable Signal Extraction in Spectroscopy

Younsik Kim and Changyoung Kim

PRX Intelligence 1, 023005 (2026) - Published 20 October, 2026

A denoising network that reports a calibrated uncertainty alongside every data point allows 12-second photoemission scans to yield superconducting gap values with meaningful error bars, turning deep learning from a visualization aid into a quantitative measurement tool.

Fidelity of Machine-Learned Potentials: Quantitative Assessment for Protonated Oxalate

Chen Qu, Paul L. Houston, Qi Yu, Apurba Nandi, Joel M. Bowman, Valerii Andreichev, Silvan Käser, and Markus Meuwly

PRX Intelligence 1, 023006 (2026) - Published 21 October, 2026

Several stress tests are utilized to assess the accuracy of two widely used machine-learned potential approaches.

Transformer Neural-Network Quantum States for Lattice Models of Spins and Fermions: Application to the Ancilla Layer Model

Riccardo Rende, Alexander Nikolaenko, Luciano Loris Viteritti, Subir Sachdev, and Ya-Hui Zhang

PRX Intelligence 1, 023007 (2026) - Published 22 October, 2026

A Transformer-based neural quantum state unifies spin and fermionic degrees of freedom in a single variational framework, achieving high accuracy in one dimension and extending naturally to challenging two-dimensional systems.

Detailed Balance in Large-Language-Model-Driven Agents

Zhuo-Yang Song, Qing-Hong Cao, Ming-xing Luo, and Hua Xing Zhu

PRX Intelligence 1, 023008 (2026) - Published 27 October, 2026

Analysis of the transition probabilities between large language model generated states shows that the dynamics of LLMs tend toward detailed balance.

Dressing Composite Fermions with Artificial Intelligence

Mytraya Gattu

PRX Intelligence 1, 023009 (2026) - Published 28 October, 2026

A nonperturbative approach to Landau-level mixing in fractional quantum Hall liquids achieves competitive accuracy with high computational efficiency.

Interpretable Artificial Intelligence Analysis of Strongly Correlated Electrons

Changkai Zhang (张昌凯) and Jan von Delft

PRX Intelligence 1, 023010 (2026) - Published 29 October, 2026

A tailored AI workflow learns latent patterns in tensor-network simulated snapshots of strongly correlated electrons in the 2D Hubbard model, enabling estimates of temperature and electron density with potential applications to ultracold atom simulators.

Learning Activator-Inhibitor Dynamics at the Cell Cortex with Neural Likelihood Ratio Estimation

Ondrej Maxian, Edwin Munro, and Aaron R. Dinner

PRX Intelligence 1, 023011 (2026) - Published 3 November, 2026

Neural simulation-based inference makes possible the identification and differentiation of hypotheses for how cell-scale organization emerges from molecular factors.

Machine-Learned Particle Flow as a Foundation Model for Collider Physics

Farouk Mokhtar, Joosep Pata, Michael Kagan, and Javier Duarte

PRX Intelligence 1, 023012 (2026) - Published 4 November, 2026

Machine learning models developed for core physics tasks, such as particle reconstruction, can double as foundation models.

Stochastic Thermodynamics for Autoregressive Generative Models: A Non-Markovian Perspective

Takahiro Sagawa

PRX Intelligence 1, 023013 (2026) - Published 5 November, 2026

A general framework which introduces the entropy production for generative autoregressive models establishes a bridge between these models and stochastic thermodynamics.

Achieving Angular-Momentum Conservation with Physics-Informed Neural Networks in Computational Relativistic Spin Hydrodynamics

Hidefumi Matsuda, Koichi Hattori, and Koichi Murase

PRX Intelligence 1, 023014 (2026) - Published 12 November, 2026

Physics-informed neural networks enable numerical simulations of relativistic spin hydrodynamics with strict angular-momentum conservation, which is essential for studying the rotational viscous effect that drives the mutual conversion between spin and orbital angular momentum.

lara-hpc: Validation-Driven Agentic Supercomputer Workflows for Atomistic Modeling

William Dawson, Louis Beal, Yoann Curé, Giuseppe Fisicaro, Dorian Rolland, and Luigi Genovese

PRX Intelligence 1, 025001 (2026) - Published 10 November, 2026

A validation-driven agentic framework is demonstrated that enables reliable workflow generation for atomistic simulations on high performance computing systems.

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