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Characterization of blood velocity in arteries using a combined analytical and Doppler imaging approach

Bchara Sidnawi1,2, Zhen Chen3, Chandra Sehgal3, Sridhar Santhanam1, and Qianhong Wu1,2,*

  • 1Department of Mechanical Engineering, Villanova University, Villanova, Pennsylvania 19085, USA
  • 2Cellular Biomechanics and Sport Science Laboratory, Villanova University, Villanova, Pennsylvania 19085, USA
  • 3Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

  • *Author to whom all correspondence should be addressed: qianhong.wu@villanova.edu
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Phys. Rev. Fluids 4, 053101 – Published 13 May, 2019

DOI: https://doi.org/10.1103/PhysRevFluids.4.053101

Abstract

We report an experimental and analytical approach to characterize the pulsatile blood flow field based on Doppler ultrasound imaging of the carotid and brachial arteries. The diameter-averaged velocity, obtained from the instantaneous velocity histograms extracted from the Doppler waveform, was adapted to the solution of a pulsatile flow in a pipe, from which the instantaneous velocity profiles were predicted and compared to local velocity measurements in the carotid and brachial arteries of four healthy human subjects. Very good agreement as demonstrated by the regression slope of 0.97 and the near-zero intercept was observed between the spatiotemporal flow field predictions and local velocity measurements at specific distances from the vessel wall. Near-real-time in vivo measurements statistically demonstrate that the analytical and experimental approach presented herein precisely captures the pulsatile blood flow behavior in large blood vessels.

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Outline

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Phys. Rev. Fluids 4, 053101– Published 13 May, 2019
  • Received 4 October 2018
Article part of CHORUS
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