This year, 2020, is the 50th anniversary of Physical Review C, which evolved from a section of its parent journal, The Physical Review, to one of the most read and trusted journals for nuclear physics. As part of the anniversary celebration, we are putting together a collection of milestone papers that remain central to developments in the field of nuclear physics. These papers announce major discoveries or open up new avenues of research. They would not have come to our journal, had the community not trusted and upheld the top-shelf quality of what PRC has traditionally published and intends to publish in the future.








































